IGE Therapeutics, Inc.

SAN DIEGO, CA 92121

SBIR Award Summary

Total Number of Awards 11
Total Value of Awards $5.02MM
First Award Date 09/30/01
Most Recent Award Date 06/01/17

Key Personnel

Last Name Name Awards Contact
Chen Swey-Shen Chen 11
Hsu Daniel K Hsu 2
Liu Fu-Tong Liu 2

11 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PAR-14-088
Budget: 06/01/17 - 05/31/18

? DESCRIPTION (provided by applicant): Allergic asthma is a multi-faceted inflammatory disease in the lung. IgE and Th2-mediated inflammation play a critical role in extrinsic allergic asthma. Our labs have identified naturally processed IgE cytotoxic peptides (nECP) on IgE producing cells, which serve as CTL vaccine. The feasibility of usin...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PAR-14-088
Budget: 03/01/17 - 02/28/18

ABSTRACT/SUMMARY Immunoglobulin E (IgE) in the lung plays a key role in allergic asthmatic inflammation. Asthmatic patients also exhibit elevated serum IgE levels, which may re-equilibrate with the lung IgE pool or enhance IgE-mediated allergic asthma. A seminal finding of IgE downregulation by active IgE immunization was first reported in our l...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PAR-14-088
Budget: 06/15/16 - 05/31/17

? DESCRIPTION (provided by applicant): Allergic asthma is a multi-faceted inflammatory disease in the lung. IgE and Th2-mediated inflammation play a critical role in extrinsic allergic asthma. Our labs have identified naturally processed IgE cytotoxic peptides (nECP) on IgE producing cells, which serve as CTL vaccine. The feasibility of using...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-134
Budget: 09/01/10 - 08/31/12

DESCRIPTION (provided by applicant): IgE-mediated allergic diseases, afflicting 25% of the US population, are manifested as allergic asthma, rhinitis, food allergy, atopic dermatitis, and anaphylaxis. In addition to symptomatic treatments with various classical pharmaceutical agents, there are two main modalities of therapeutic treatment target...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-135
Budget: 07/01/10 - 06/30/12

DESCRIPTION (provided by applicant): Eczema affects a wide population age group, and prevalence of the disease has increased two- to three-fold during the past three decades in industrialized countries, where the current incidence in children is estimated to be 15-20%. Studies suggest that eczema is a complex disease, involving multiple immunol...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-134
Budget: 09/30/09 - 08/31/10

DESCRIPTION (provided by applicant): IgE-mediated allergic diseases, afflicting 25% of the US population, are manifested as allergic asthma, rhinitis, food allergy, atopic dermatitis, and anaphylaxis. In addition to symptomatic treatments with various classical pharmaceutical agents, there are two main modalities of therapeutic treatment target...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-135
Budget: 07/23/09 - 06/30/10

DESCRIPTION (provided by applicant): Eczema affects a wide population age group, and prevalence of the disease has increased two- to three-fold during the past three decades in industrialized countries, where the current incidence in children is estimated to be 15-20%. Studies suggest that eczema is a complex disease, involving multiple immunol...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 01/01/04 - 12/31/04

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 01/01/03 - 12/31/03

DESCRIPTION (provided by applicant): IgE-mediated allergic asthma, rhinitis, food allergy, atopic dermatitis, anaphylaxis cost annual 18 billions in medical costs and loss of productivity in this country. Regulation of IgE production by B cells is orchestrated by Th2 cytokines, and cognate interactions of B cells and Th2. IL-4 contributes to I...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/02 - 08/31/03

DESCRIPTION (Provided by the applicant): IgE-mediated allergic asthma, rhinitis, food allergy, atopic dermatitis, anaphylaxis cost annual 18 billions in medical costs and loss of productivity in this country. Regulation of IgE production by B cells is orchestrated by Th2 cytokines. This paradigm dictates a treat...

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