GEM Pharmaceuticals, LLC

Birmingham, AL 35244

SBIR Award Summary

Total Number of Awards 5
Total Value of Awards $1.04MM
First Award Date 05/15/00
Most Recent Award Date 09/15/05

Key Personnel

Last Name Name Awards Contact
Olson Richard D Olson 4
Wingett Denise G Wingett 1

5 Awards Won

Phase 1 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 09/15/05 - 08/31/06

DESCRIPTION (provided by applicant): Psoriasis is a common immune-mediated disease that affects approximately 2% of the US and European populations and significantly impacts the quality of life. T cells are recognized as primary mediators of the disease and new generation therapies aimed at eliminating reactive T cells or interfering with the im...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/04 - 08/31/05

DESCRIPTION (provided by applicant): Paclitaxel (Taxol) and doxorubicin (DOX, Adriamycin) are chemotherapeutic drugs used in treatment of metastatic breast cancer. When used individually, they produce a 30-40 percent response rate. When combined, using high doses of DOX (450-550 mg/m2), the response rate is increased to 85-95 percent. This repre...

Phase 2 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 06/01/03 - 09/30/04

Anthracyclines such as doxorubicin and daunorubicin are valuable anti- cancer drugs but their clinical utility is compromised by cumulative dose-dependent by a cumulative dose dependent cardiotoxicity. Anthracycline cardiotoxicity has been linked to free radical damage via mechanisms that involve disruption of iron regulation and formation of su...

Phase 2 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 06/01/02 - 05/31/03

Anthracyclines such as doxorubicin and daunorubicin are valuable anti- cancer drugs but their clinical utility is compromised by cumulative dose-dependent by a cumulative dose dependent cardiotoxicity. Anthracycline cardiotoxicity has been linked to free radical damage via mechanisms that involve disruption of iron regulation and formation of su...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 05/15/00 - 05/14/01