Biomod Surfaces

Newbury, MA 01951

SBIR Award Summary

Total Number of Awards 8
Total Value of Awards $1.65MM
First Award Date 06/23/00
Most Recent Award Date 07/15/04

Key Personnel

Last Name Name Awards Contact
Dempsey Donald J Dempsey 6
Phaneuf Matthew M Phaneuf 2

8 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/15/04 - 03/31/07

DESCRIPTION (provided by applicant):Cardiac valve replacement using prosthetic valves is indicated when progression of degenerative disease, annular dilatation or bacterial infection of the native valve results in valvular dysfunction. Bacterial infection is a major complication associated with implantation of these prosthetic valves. Infections...

Phase 2 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 05/01/03 - 04/30/04

Medium (6-8mm) and small (<5mm) internal diameter prosthetic grafts continue to have clinically unacceptable high failure rates. In phase I, an ionic polyurethane-sealed Dacron vascular graft (PEU-D) with reduced water permeation, excellent physical properties and co-valently bound anti-thrombin (recombinant hirudin of rHir) and mitogenic (vascu...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 01/10/03 - 06/30/04

DESCRIPTION (provided by applicant):Cardiac valve replacement using prosthetic valves is indicated when progression of degenerative disease, annular dilatation or bacterial infection of the native valve results in valvular dysfunction. Bacterial infection is a major complication associated with implantation of these prosthetic valves. Infections...

Phase 2 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 05/01/02 - 04/30/03

Medium (6-8mm) and small (<5mm) internal diameter prosthetic grafts continue to have clinically unacceptable high failure rates. In phase I, an ionic polyurethane-sealed Dacron vascular graft (PEU-D) with reduced water permeation, excellent physical properties and co-valently bound anti-thrombin (recombinant hirudin of rHir) and mitogenic (vascu...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 05/01/02 - 04/30/03

There is no small-diameter vascular prosthesis that is capable of emulating the biologic and physical properties of the normal arterial wall. The goal of this proposal is to develop a small-diameter prosthetic vascular graft using nanofiber technology. Our hypothesis is creating a nanofibrous vascular graft by electrospinning an ionic polyuretha...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/01/01 - 12/31/01

DESCRIPTION (Verbatim from the Applicant's Abstract): Cardiac valve replacement using prosthetic valves is indicated when progression of degenerative disease or bacterial infection of the native valve results in valvular dysfunction, thereby impacting on cardiac output. Bacterial infection is a major complic...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 07/01/00 - 06/30/01

Medium (6-8mm) and small (<5mm) internal diameter prosthetic grafts continue to have clinically unacceptable high failure rates. Dacron vascular grafts have had limited use due to sealing of the porous graft matrix with proteins that have numerous adverse effects. Our objective is to create a sealed Dacron vascular graft using a polyether-based ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/23/00 - 12/22/00

Mechanical heart valve failure is primarily due to thrombosis and thromboembolic complications. Titanium (Ti) has advantageous bulk and surface properties but is still susceptible to surface thrombus formation. Our hypothesis is the layer of chemisorbed oxygen or oxide layer established on the Ti surface can be utilized to form Ti-O-Si bonds on...