Virogenomics, Inc.

Portland, OR 97223

SBIR Award Summary

Total Number of Awards 39
Total Value of Awards $10.4MM
First Award Date 08/01/98
Most Recent Award Date 08/01/17

39 Awards Won

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-16-303
Budget: 08/01/17 - 07/31/18

This is a Phase I STTR to investigate the preclinical efficacy of a novel immunomodulator, DR?1-MOG, in a clinically relevant thromboembolic stroke model in mice. We have previously shown that T cells are activated after stroke, infiltrate brain, and exacerbate ischemic brain damage. Strategies that reduce T cell activation and brain tissue infi...

Phase 2 STTR

Agency: Department of Health & Human Services
Topic: PA-16-303
Budget: 07/17/17 - 06/30/18

PROJECT SUMMARY/ABSTRACT Our recently completed Phase 1 animal studies demonstrated the ability of our novel second generation partial (p)MHC construct, DR?1-hMOG-35-55, to treat acute and chronic EAE with potency comparable to the parent RTL1000 molecule (pDR2-MOG-35-55) in matched DR2-Tg mice and in DR2 negative mismatched mice. Having met our...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PAR-13-327
Budget: 09/21/16 - 08/31/17

Project Summary All cancer patients live with the possibility that their cancer will recur and many patients develop secondary cancers as a result of treatments used for their original cancer. This project addresses the problem of drug resistance and disease recurrence in cancer by leveraging unique, single nanoparticle techniques to identify ra...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-14-072
Budget: 02/01/16 - 01/31/17

? DESCRIPTION (provided by applicant): Our laboratory discovered and is developing partial (p)MHC class II constructs (pMHC) as a possible immunotherapy for multiple sclerosis (MS). pMHC containing the extracellular domains of the MS risk factor, HLA-DR2, linked covalently to the encephalitogenic 35-55 peptide of myelin oligodendrocyte glyco...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-14-072
Budget: 07/01/15 - 06/30/16

DESCRIPTION (provided by applicant): Methamphetamine (MA) dependence is associated with long-term damage to regions of the brain that control cognitive and psychiatric function. One-third to one-half of MA dependent adults experience persistent cognitive and other psychiatric disorders up to three years or longer into remission. The neuropsychia...

Phase 2 STTR

Agency: Department of Health & Human Services
Topic: PA-11-097
Budget: 08/01/13 - 07/31/14

DESCRIPTION (provided by applicant): This application is a Phase II STTR to further the study of a novel therapeutic intervention for ischemic stroke. Phase I investigated the mechanism of protection against ischemic stroke provided by the novel "designer" therapy, recombinant T cell receptor ligand (RTL), a selective modulator of the inflammato...

Phase 2 STTR

Agency: Department of Health & Human Services
Topic: PA-11-097
Budget: 08/01/12 - 07/31/13

DESCRIPTION (provided by applicant): This application is a Phase II STTR to further the study of a novel therapeutic intervention for ischemic stroke. Phase I investigated the mechanism of protection against ischemic stroke provided by the novel "designer" therapy, recombinant T cell receptor ligand (RTL), a selective modulator of the inflammato...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-09-127
Budget: 04/01/12 - 10/31/13

DESCRIPTION (provided by applicant): Virogenomics is currently developing a portable, electrochemical device for rapid disease diagnosis of multiple indications. The basis of our approach is a patent-pending electrochemical immunoassay performed on patterned electrode arrays, and we take advantage of existing microelectronics technology to crea...

Phase 2 SBIR

Agency: National Science Foundation
Topic: BC-2012
Budget: 01/01/12 - 12/31/12
PI: Jeff King

This Small Business Innovation Research (SBIR) Phase II project aims to create better diagnostic testing for drug, food, and environmental allergies. If successful, it would be transformative in the clinical diagnosis of allergy diseases by enabling rapid evaluation at the doctor?s office in a format that is significantly preferable to skin-pric...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-09-115
Budget: 03/01/11 - 02/28/13

DESCRIPTION (provided by applicant): Respiratory syncytial virus (RSV)-caused disease represents a significant health care burden worldwide. The RSV infects virtually all children throughout the world in both developed and developing countries. Re-infection is common because natural infection does not induce lasting immunity. Also, severe RSV i...

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