Biotechplex Corporation

1205 Linda Vista Drive, Suite A
San Marcos, CA 92078

SBIR Award Summary

Total Number of Awards 30
Total Value of Awards $6.57MM
First Award Date 02/01/98
Most Recent Award Date 08/01/08

Key Personnel

Last Name Name Awards Contact
Wong Lid B Wong 15
Yeates Donovan B Yeates 5
Mao Hua Mao 8
Yuan Weihua Yuan 1
Yi Jinghai Yi 1

30 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-20
Budget: 08/01/08 - 07/31/10

DESCRIPTION (provided by applicant): It has been estimated that 16% of new drugs will be delivered via the respiratory tract for the treatment of both respiratory and non-respiratory diseases. These agents include surfactant, antibiotics, mucokinetics, peptides, anticancer agents, and biologics. Whereas there are excellent nebulizers for the del...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-20
Budget: 09/25/07 - 07/31/08

DESCRIPTION (provided by applicant): It has been estimated that 16% of new drugs will be delivered via the respiratory tract for the treatment of both respiratory and non-respiratory diseases. These agents include surfactant, antibiotics, mucokinetics, peptides, anticancer agents, and biologics. Whereas there are excellent nebulizers for the del...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/01/07 - 03/31/09

DESCRIPTION (provided by applicant): BioTechPlex proposes to develop a high content, high throughput, cell-based screening system for drug discovery using epithelial cells. This system will enable the dynamic responses of multiple cellular fluorophore-reportable molecular species to be simultaneously measured in a 96 well plate. The dynamic resp...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 03/01/07 - 02/28/09
PI: Hua Mao

DESCRIPTION (provided by applicant): Persons with asthma are characterized by hyper-responsive airways, tissue inflammation, airway remodeling and the consequent impaired mucociliary transport. This proposal is based on the hypothesis that the IL-4 and IL-13 activated STAT6 pathway is up-regulated in persons with atopic asthma and subsequently r...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/06 - 06/30/07

DESCRIPTION (provided by applicant): BioTechPlex proposes to develop a high content, high throughput, cell-based screening system for drug discovery using epithelial cells. This system will enable the dynamic responses of multiple cellular fluorophore-reportable molecular species to be simultaneously measured in a 96 well plate. The dynamic resp...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 03/08/06 - 02/28/07
PI: Hua Mao

DESCRIPTION (provided by applicant): Persons with asthma are characterized by hyper-responsive airways, tissue inflammation, airway remodeling and the consequent impaired mucociliary transport. This proposal is based on the hypothesis that the IL-4 and IL-13 activated STAT6 pathway is up-regulated in persons with atopic asthma and subsequently r...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/15/05 - 03/30/06
PI: Hua Mao

DESCRIPTION (provided by applicant): There is a critical need and very large market for a miniature ultra-low pressure transducer to monitor pressure within confined body spaces for both animal and human application. Thus, BioTechPlex proposes to develop such a pressure sensor system with wide dynamic range and ultra-fine resolution. This Fib...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/04 - 12/31/05

DESCRIPTION (provided by applicant): Of the 30 million US patients who suffer from respiratory disorders, over 4 million require frequent inhaled medication. Therapy sessions can last from several minutes to 3 hours. In addition, inhaled drugs are increasingly used to deliver drugs for systemic disorders. The utility of present devices is gen...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/04 - 07/31/06
PI: Hua Mao

DESCRIPTION (provided by applicant): BioTechPlex proposes to develop mammalian tracheal/bronchial airway epithelial cell line, CILSCREEN TM, specifically for high throughput screening. This is based on physiological functional assays. BioTechPlex has accomplished all the proposed Phase I objectives. A) Successfully developed techniques to cultur...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/01/04 - 06/30/06

DESCRIPTION (provided by applicant): BioTechPlex proposes to develop a Transmembrane Water and Ion Measurement System (TWIMS) to measure miniscule water fluxes across biological membranes in conjunction with their electro-physiological properties. BioTechPlex has accomplished all the objectives proposed in Phase I. A) Developed a novel light ...

Load More