Lucigen Corporation

Middleton, WI 53562
http://lucigen.com

SBIR Award Summary

Total Number of Awards 74
Total Value of Awards $23.8MM
First Award Date 05/15/98
Most Recent Award Date 02/08/17

74 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-15-052
Budget: 02/08/17 - 12/31/17

? DESCRIPTION (provided by applicant): In this Phase I proposal, we plan to develop two technologies to dramatically increase the expression and crystallization of properly folded recombinant membrane proteins from mammalian cell culture. The most common methods to produce high yields of recombinant proteins at low cost rely on bacterial, yea...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-15-269
Budget: 07/01/16 - 06/30/17

Expensive equipment, highly-trained personnel, and the need for a clinical laboratory setting precludesroutine nucleic acid testing (NAT) for infectious disease in most of the developing world and even in manyresource-limited parts of the United States, leading to wide disparities in health care worldwide. A fast,sensitive, low cost but a facile...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-11-335
Budget: 04/01/16 - 03/31/17

? DESCRIPTION (provided by applicant): The human transcriptome is significantly more complex than its cognate genome, due to the hundreds of thousands of possible isoforms, allele-specific expression issues, variable RNA editing changes, and differential expression patterns spanning cell types, developmental stages, and physiological stresse...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-11-335
Budget: 03/01/16 - 02/28/17

? DESCRIPTION (provided by applicant): A post-antibiotic era of multiple drug resistance has begun to threaten the health and well-being of mankind. A crucial limitation in economically converting untapped natural product potential to final scalable production is the lack of next-generation tools to effectively access the full medicinal impac...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-14-071
Budget: 03/01/16 - 02/28/17

Summary/abstract The proteins encoded by the human genome may participate in as many as 200,000 pairwise protein interactions, and ?nearly every major process in a cell is carried out by assemblies of 10 or more interlocking protein molecules? (Bruce Alberts, Cell 1998). However, there are no commercially available expression systems for regulat...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-15-052
Budget: 01/01/16 - 12/31/16

? DESCRIPTION (provided by applicant): In this Phase I proposal, we plan to develop two technologies to dramatically increase the expression and crystallization of properly folded recombinant membrane proteins from mammalian cell culture. The most common methods to produce high yields of recombinant proteins at low cost rely on bacterial, yea...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: RFA-DE-15-001
Budget: 09/05/15 - 09/04/16

DESCRIPTION (provided by applicant): The human Papilloma Virus (HPV) causes a wide variety of diseases in humans including squamous papilloma, focal epithelial hyperplasia, verruca vulgaris and condyloma acuminatum. In addition to benign diseases, HPV infection is implicated as an etiologic agent in malignancies including cervical and anogenital...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-11-335
Budget: 08/10/15 - 03/31/16

DESCRIPTION (provided by applicant): The human transcriptome is significantly more complex than its cognate genome, due to the hundreds of thousands of possible isoforms, allele-specific expression issues, variable RNA editing changes, and differential expression patterns spanning cell types, developmental stages, and physiological stresses. Ne...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic: PA-11-335
Budget: 04/20/15 - 03/31/16

DESCRIPTION (provided by applicant): The human transcriptome is significantly more complex than its cognate genome, due to the hundreds of thousands of possible isoforms, allele-specific expression issues, variable RNA editing changes, and differential expression patterns spanning cell types, developmental stages, and physiological stresses. Ne...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-14-071
Budget: 03/03/15 - 02/29/16

Summary/abstract The proteins encoded by the human genome may participate in as many as 200,000 pairwise protein interactions, and ?nearly every major process in a cell is carried out by assemblies of 10 or more interlocking protein molecules? (Bruce Alberts, Cell 1998). However, there are no commercially available expression systems for regulat...

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