Cocensys, Inc.

Irvine, CA 92618

SBIR Award Summary

Total Number of Awards 6
Total Value of Awards $0.0
First Award Date 09/05/97
Most Recent Award Date 07/27/99

Key Personnel

Last Name Name Awards Contact
Guastella John Guastella 1
Whittemore Edward Reed Whittemore 1
Ilyin Victor I Ilyin 1
Upasani Ravindra B Upasani 1
Konkoy Christopher S Konkoy 1
Xue Dong Xue 1

6 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/27/99 - 04/30/00
PI: Dong Xue

DESCRIPTION: (Verbatim from the Applicant's Abstract) Stroke is the number one cause of adult disability and the third leading cause of death in the USA. There remains an urgent need for effective stroke therapies. Caspases are a family of cysteine proteases that play key roles in mediating inflammation and apoptos...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/15/99 - 11/14/99

DESCRIPTION: (Verbatim from the Applicant's Abstract) The pharmaceutical treatment of stroke and head trauma has been an elusive goal. Recent studies suggest that blockade of the AMPA class of glutamate receptors may limit neuronal degeneration following stroke/neurotrauma by blocking the excitotoxic cascade...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 05/17/99 - 05/16/00

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 03/15/99 - 09/15/99

Peripheral neuropathic pain is caused by trauma to the peripheral nervous system. The condition includes syndromes as diverse as diabetic neuropathy, cancer neuropathy, and trigeminal neuralgia. Neuropathic pain is largely resistant to treatment by current therapies. In the U.S. alone, as many as 3-4 million people suffer from neuropathic pain ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 03/15/99 - 09/15/99

DESCRIPTION (Adapted from the application): Acute pain states are still mainly treated with opioids, despite their side effects, which include tolerance, dependence, respiratory depression, and constipation. Chronic pain states are not managed well with current pharmacological therapies, such as selective seroton...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/05/97 - 03/04/98

Apoptosis, or programmed cell death, is thought to play an important role in the loss of neurons due to ischemic stroke and other neurodegenerative conditions. Apoptosis has also been implicated in the death of cells occurring in certain immune disorders, polycystic kidney disease, and cardiac myopathy. The I...