Imgenex Corporation

San Diego, CA 92121

SBIR Award Summary

Total Number of Awards 13
Total Value of Awards $1.05MM
First Award Date 09/15/97
Most Recent Award Date 07/10/03

Key Personnel

Last Name Name Awards Contact
Singh Sujay K Singh 9
Dias Peter B Dias 3
Barnhart Kerry M Barnhart 1

13 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/10/03 - 06/30/04

DESCRIPTION (provided by applicant): Osteoporosis is a major health problem affecting nearly 1.5 million people every year. The reduction of sex hormone levels in both men and women increase production of certain factors that lead to osteoporosis. One-third of all post-menopausal Caucasian women experience at least osteoporotic fracture during t...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 05/01/03 - 10/31/03

DESCRIPTION (provided by applicant): Small interfering RNAs (siRNAs) have gained much attention for their powerful ability to suppress gene expression. Introduction of double-stranded RNA (dsRNA), that are homologous in sequence to a gene, has proven to suppress that gene's expression through a process known as RNA interference (RNAi); this proc...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/20/02 - 09/19/03

DESCRIPTION (provided by applicant): Osteoporosis is a major health problem affecting nearly 1.5 million people every year. The reduction of sex hormone levels in both men and women increase production of certain factors that lead to osteoporosis. One-third of all menopausal women experience at least one osteoporotic fracture during their lifeti...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/02 - 02/28/03

DESCRIPTION (provided by applicant): Comprehensive study of the function and interrelationships of the proteins controlling the metabolism of the neurotransmitter GABA is important not only for understanding the basic biology of neuronal signaling, but also for uncovering potential new therapies for many severe neurological disorders. Such study...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 05/07/02 - 11/30/02

DESCRIPTION (provided by applicant): Efforts to sequence various genomes have provided a wealth of new biological data, but have exacerbated a growing deficit in tools to study protein function and interrelationships. This may be particularly true in neurobiology where many new pathways have been identified, but reagents, such as antibodies, sti...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/02 - 08/31/02

Utilizing the full scientific potential of the completed and on-going genome projects will require advances in technologies used to create research tools for functional genomics. Advances in the systems and techniques to create monoclonal antibodies in particular will be crucial importance, due to the critical role thee molecules play in unravel...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/00 - 02/28/01

Osteoporosis is a major health problem affecting nearly 1.5 million people every year. One-third of all post-menopausal Caucasian women experience at least one osteoporotic fracture during their lifetime. The reduction of sex hormone levels in both men and women increases production of certain factors that lead to osteoporosis. An imbalance betw...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 02/01/00 - 01/31/01

Telomerase is an enzyme that catalyzes the replacement of short telomeric repeats (TTAGGG)n at the ends of chromosomes and thus maintains the length of telomeres. Loss of telomeric DNA results in senescence whereas strong telomerase activity results in cell immortality. Telomerase Is now established as a sensitive and specific marker for cancer....

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/99 - 08/31/00

Serotonin (5-hydroxytryptamine; 5-HT) mediates many central and peripheral nervous functions by its interaction with specific neuronal receptors. The 5-HT receptors are implicated in various normal physiological responses, e.g., smooth muscle contraction, platelet aggregation, aldosteron...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/98 - 04/30/00

It is difficult to diagnose poorly differentiated rhabdomyosarcomas from other small round cell tumors and to identify subtypes of rhabdomyosarcomas that confer poor prognosis. Through SBIR Phase-I funding we developed and characterized monoclonal antibodies that are highly specific to MyoD...

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