Claragen, Inc.

Rockville, MD 20852

SBIR Award Summary

Total Number of Awards 5
Total Value of Awards $1.05MM
First Award Date 01/17/98
Most Recent Award Date 09/30/03

Key Personnel

Last Name Name Awards Contact
Pilon Aprile L Pilon 5

5 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/03 - 03/31/05

DESCRIPTION (provided by applicant): Recombinant human CC 10 is a novel therapeutic agent that is currently in clinical development for prevention of bronchopulmonary dysplasia (BPD) in preterm infants. CC10 is also known as clara cell secretory protein (CCSP) or uteroglobin and is produced primarily by tracheal and bronchial epithelia. The prot...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 04/02/01 - 12/31/02

DESCRIPTION (Scanned from the applicant's description): The proposed study involves an evaluation of the dose response to recombinant human CC10 in the preterm lamb, a surfactant-dependent model of neonatal/infant respiratory distress syndrome (IRDS). The preterm lamb model was used in the clinical develop...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/00 - 05/31/02

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/09/00 - 12/31/01

The purpose of the proposed study is to evaluate the effectiveness of two potential anti-tumor agents, both separately and in combination, in an adoptive transfer model of lung cancer. The first agent is recombinant human CC10, which has recently been shown to have anti-metastatic and tumor suppressive effects on a variety of human tumor cell ty...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 01/17/98 - 07/16/98

A new protein therapy for the treatment and/or prevention of broncho- pulmonary dysplasia (BPD) in premature neonates is proposed. BPD is a long term inflammatory response to lung tissue damage initiated in the treatment of respiratory distress syndrome in premature infants, with surfactant and hyperbar...