Vectramed, Inc.

Princeton, NJ 08540

SBIR Award Summary

Total Number of Awards 8
Total Value of Awards $1.02MM
First Award Date 07/25/97
Most Recent Award Date 09/30/01

Key Personnel

Last Name Name Awards Contact
Pachence James M Pachence 8

8 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/01 - 03/31/02

DESCRIPTION (Verbatim from the Applicant's Abstract): Surgical intervention, by its very nature, results in tissue damage that triggers the formation of fibrotic scar tissue as part of the normal wound healing response. Although inflammation and production of extracellular matrix components is necessary for normal ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 05/01/00 - 01/31/02

Surgical intervention, by its very nature, results in tissue damage that triggers the formation of fibrotic sear tissue as part of the normal wound healing response. Although inflammation and production of extracellular matrix components is necessary for normal wound healing, adhesions may also occur which can lead to significant clinical compl...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/00 - 03/31/01

In our previous studies, proline analogues such as cis-4-hydroxy-L-proline (cHyp, a potent inhibitor of collagen synthesis) have been attached to a class of water soluble polymers which were found to sustain release, reduce toxicity, and increase antifibrotic potency. The water soluble polymer consists of an alternating copolymer of low molecula...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/99 - 03/29/00

A series of water soluble polymers have been developed, consisting of strictly alternating copolymers of polyethylene glycol (PEG, MW 1000 to 8000) and the amino acid lysine (Lys). When Lys is used as the amino acid component, a free carboxylic acid pendent group at each monomeric repeat unit is used to couple active agents. A series of studies ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 05/01/99 - 04/30/00

Surgical intervention, by its very nature, results in tissue damage that triggers the formation of fibrotic sear tissue as part of the normal wound healing response. Although inflammation and production of extracellular matrix components is necessary for normal wound healing, adhesions may also occur which can lead to significant clinical compl...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/99 - 03/31/00

In our previous studies, proline analogues such as cis-4-hydroxy-L-proline (cHyp, a potent inhibitor of collagen synthesis) have been attached to a class of water soluble polymers which were found to sustain release, reduce toxicity, and increase antifibrotic potency. The water soluble polymer consists of an alternating copolymer of low molecula...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/97 - 03/31/98

DESCRIPTION (Adapted from applicant's abstract): Surgical intervention, by its very nature, results in tissue damage that triggers the formation of fibrotic scar tissue as part of the normal wound healing response. Although inflammation and production of extracellular matrix components is necessary for normal...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/25/97 - 05/31/98

DESCRIPTION: (adapted from applicant's abstract) The principal aim of this proposal is to deliver a sustained release, polymeric agent to prevent collagen accumulation in hypertensive blood vessels. The polymer, a backbone of alternating PEG2000 and lysine with the proline analogue cis-4-hydroxy-...