Decode Biostructures

Bainbridge Island, WA 98110

SBIR Award Summary

Total Number of Awards 13
Total Value of Awards $2.77MM
First Award Date 07/23/98
Most Recent Award Date 09/21/02

Key Personnel

Last Name Name Awards Contact
Stewart Lance J Stewart 8
Nollert-Von Specht Peter K Nollert-Von Specht 1
Kim Hidong Kim 4

13 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/21/02 - 11/30/03

DESCRIPTION (provided by applicant): Human topoisomerase I (topo I) is the sole intracellular target of camptothecin (CPT) and other "topo I poisons," some of which are among the most promising anticancer drugs ever identified. Emerald BioStructures, Inc. has successfully completed a Phase I SBIR research program that so...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/01/02 - 05/31/03

DESCCRIPTION: Applicant?s abstract) An integrated, automated protein crystallization system,RoboHTC (Robotic High-Throughput Crystallization), will be developed, consisting of software and hardware tools suitable for large-scale protein crystallography projects, such as structural genomics. These tools will also be highly modular, allowing indiv...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 03/15/02 - 09/14/03

Information derived from the three-dimensional structure of proteins has been of increasing importance in the development of pharmaceuticals. Structures determined using 3-D X-ray crystallography have been vital in the development of anti-AIDS and anti-cancer agents. Membrane proteins constitute a large fraction of genes, and are the target of a...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/20/01 - 08/31/02

DESCRIPTION (provided by applicant): Human topoisomerase I (topo I) is the sole intracellular target of camptothecin (CPT) and other "topo I poisons," some of which are among the most promising anticancer drugs ever identified. Emerald BioStructures, Inc. has successfully completed a Phase I SBIR research program that so...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/01/01 - 05/31/02

DESCCRIPTION: Applicant?s abstract) An integrated, automated protein crystallization system,RoboHTC (Robotic High-Throughput Crystallization), will be developed, consisting of software and hardware tools suitable for large-scale protein crystallography projects, such as structural genomics. These tools will also be highly modular, allowing indiv...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/01/01 - 05/31/02

DESCCRIPTION: Applicant?s abstract) An integrated, automated protein crystallization system,RoboHTC (Robotic High-Throughput Crystallization), will be developed, consisting of software and hardware tools suitable for large-scale protein crystallography projects, such as structural genomics. These tools will also be highly modular, allowing indiv...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: RFA-CA-98-22
Budget: 07/01/00 - 06/30/01

Human topoisomerase I (topoI) is the sole intracellular target of camptothecin (CPT) and other "topo I poisons," some of which are among the most promising anticancer drugs ever identified. Emerald BioStructures, Inc. is actively engaged in a Phase I SBIR study that seeks to elucidate the X-ray crystal structure(s) of human topo I in complex wit...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 03/01/00 - 02/28/01

Emerald BioStructures, Inc. Is developing an integrated set of crystallization research tools and software that are designed for high-throughput crystallization by robots as well as the standard laboratory use by individual researchers with little or no prior crystallization research experience. These tools provide a streamlined and systema...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: RFA-CA-98-22
Budget: 07/01/99 - 06/30/00

Human topoisomerase I (topoI) is the sole intracellular target of camptothecin (CPT) and other "topo I poisons," some of which are among the most promising anticancer drugs ever identified. Emerald BioStructures, Inc. is actively engaged in a Phase I SBIR study that seeks to elucidate the X-ray crystal structure(s) of human topo I in complex wit...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: RFA-CA-98-22
Budget: 07/01/99 - 06/30/00

Human topoisomerase I (topoI) is the sole intracellular target of camptothecin (CPT) and other "topo I poisons," some of which are among the most promising anticancer drugs ever identified. Emerald BioStructures, Inc. is actively engaged in a Phase I SBIR study that seeks to elucidate the X-ray crystal structure(s) of human topo I in complex wit...

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