Diversified Scientific, Inc.

1601 12th Ave. S.
Birmingham, AL 35205

SBIR Award Summary

Total Number of Awards 28
Total Value of Awards $5.77MM
First Award Date 01/01/95
Most Recent Award Date 06/01/04

Key Personnel

Last Name Name Awards Contact
Christopher Gayle K Christopher 5
Singh Raj K. Singh 5 Message
Rosenblum William Rosenblum 2
Gester Thomas E. Gester 17 Message
Hamrick David T. Hamrick 5 Message
C. Gayle C. PhD 4 Message
Gayle Gayle PhD 1 Message
Gayle Gayle PhD 1 Message
Raj Singh Raj 2 Message
Cosenza Larry Cosenza 2 Message

28 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/01/04 - 09/26/04

DESCRIPTION (provided by applicant): There is a need for developing an in vitro tumorigenesis model which mimics the in vivo biology of tumors. At present, tumor studies mostly utilize monolayer cell cultures and animal-derived biomatrix systems. The commonly used Matrigel and collagen models exhibit major compositional and biological limitat...

Phase 1 SBIR

Agency: National Aeronautics and Space Administration
Topic: 04-1
Budget: 01/01/04 - 12/31/04

The proposed innovation will utilize self learning neural network technology to determine the structure of osteoporosis, immune system disease, and excess radiation DNA damage target proteins that will facilitate drug development to enhance crew health in long term space flight missions. This system is innovative because: 1) the proprietary neur...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-01-91
Budget: 09/01/02 - 08/31/03

DESCRIPTION (provided by applicant): Metastatic spread of cancer via proteolytic degradation of host biomatrix continues to be the greatest barrier to cancer cure. Two key matrix-degrading metalloproteinases (MMPs), MMP-2 and -9, are implicated in these tumor progression events in humans. They are, therefore, targets for potential anticancer dru...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/02 - 09/26/04

DESCRIPTION (provided by applicant): In our initial application we successfully argued for the need to develop a novel human biomatrix model system to examine in vitro the neovascularization process in humans. The overall goal was and is to develop and commercialize the new human bioassay system employi...

Phase 1 SBIR

Agency: National Aeronautics and Space Administration
Topic: 02-1
Budget: 01/01/02 - 12/31/02

The objective of this project is to develop a novel proprietary tool for crystallization of protein molecules and in addition to develop a multiple gene expression vector for producing protein complexes recombinantly. The novel phage display crystallization system is a high risk project that has a tremendous potential because the conditions for ...

Phase 1 SBIR

Agency: National Aeronautics and Space Administration
Topic: 02-1
Budget: 01/01/02 - 12/31/02
PI: Singh Raj

One of NASA¿s missions is to develop noninvasive models for monitoring the potentially deleterious effects of microgravity on human cell/tissue functions. Previous work has shown that gravitational changes can modify a variety of host cell-matrix interactions. Angiogenesis, an essential process for tissue growth and regeneration, is a coordinate...

Phase 2 SBIR

Agency: National Aeronautics and Space Administration
Topic: 02-2
Budget: 01/01/02 - 12/31/02

The objective of this project is to develop a novel proprietary tool for crystallization of protein molecules and in addition to develop a multiple gene expression vector for producing protein complexes recombinantly. The novel phage display crystallization system is a high risk project that has a tremendous potential because the conditions for ...

Phase 2 SBIR

Agency: National Aeronautics and Space Administration
Topic: 02-2
Budget: 01/01/02 - 12/31/02
PI: Singh Raj

One of NASA¿s missions is to develop noninvasive models for monitoring the potentially deleterious effects of microgravity on human cell/tissue functions. Previous work has shown that gravitational changes can modify a variety of host cell-matrix interactions. Angiogenesis, an essential process for tissue growth and regeneration, is a coordinate...

Phase 2 SBIR

Agency: National Aeronautics and Space Administration
Topic: 02-2
Budget: 01/01/02 - 12/31/02

We propose to develop a non-invasive, portable fluorescence-based detection system that will be capable of detecting and identifying biological pathogens commonly found in air, water, food, blood or even tissue that has been solublized in water. The innovativeness of this proposal involves the development of peptide ligands, using phage display ...

Phase 1 SBIR

Agency: National Aeronautics and Space Administration
Topic: 02-1
Budget: 01/01/02 - 12/31/02

We propose to develop a non-invasive, portable fluorescence-based detection system that will be capable of detecting and identifying biological pathogens commonly found in air, water, food, blood or even tissue that has been solublized in water. The innovativeness of this proposal involves the development of peptide ligands, using phage display ...

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