Scriptgen Pharmaceuticals, Inc.

Waltham, MA 02451

SBIR Award Summary

Total Number of Awards 3
Total Value of Awards $0.0
First Award Date 09/30/97
Most Recent Award Date 09/30/99

Key Personnel

Last Name Name Awards Contact
Pakula Andrew A Pakula 1
Wobbe Clarence Richard Wobbe 1
Harvey Thomas C Harvey 1

3 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/99 - 09/29/00

DESCRIPTION (Adapted from the application): Development of antihepatitis B viral drugs (anti-HBV drugs) with enhanced potency, efficacy, bioavailability, and a broad therapeutic index is proposed. Using SCAN technology, four classes of lead molecules were identified by a high-throughput screen as small molecule ligands...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/01/98 - 06/30/99

Two factors have contributed to the urgent need for effective new antifungal agents - the rising incidence of systemic yeast and mold infections, especially in immunocompromised individuals, and the current lack of drugs that are both fungicidal and relatively free of deleterious side effects. The aim o...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/97 - 09/29/98

This proposal focuses on the development of a novel bifunctional drug screening assay for the discovery of specific inhibitors of human h-Ras protein utilizing the proprietary ATLAS (any target ligand affinity screen) approach, which was originally developed by th P.I., Dr. Pakula Ras is a member of a la...