Copernicus Therapeutics, Inc.

Cleveland, OH 44106

SBIR Award Summary

Total Number of Awards 4
Total Value of Awards $200K
First Award Date 05/01/97
Most Recent Award Date 09/01/01

Key Personnel

Last Name Name Awards Contact
Perales Jose C Perales 1
Cooper Mark J Cooper 3

4 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/01 - 08/30/02

To develop a non-intravenous, needle-less gene transfer platform for systemic deficiency disorders, including hemophilia and alpha (1)- antitrypsin deficiency, Copernicus Therapeutics has evaluated intratracheal delivery of proprietary formulations of compacted DNA (PLASmin complexes). Our gene transfer system compacts single molecules of plasmi...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/00 - 03/31/01

Topically applied DNA vaccines may provide a safe, easy, needle-less, and cost-effective means of eliciting immunity, and has significant potential to improve world health. Recent data indicate that various skin cells can be transfected following a topical application of naked DNA. Specific immunity to DNA-encoded antigens has been observed, alt...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/08/00 - 08/07/01

Gene therapy is currently being used to treat a variety of cancers, including brain, prostate and ovarian carcinoma. However, there are many obstacles that need to be overcome if gene transfer technologies are to be fully exploited. A significant obstacle in the development of non- viral vectors is the rapid decline of gene expression in transie...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 05/01/97 - 10/31/97