Adlyfe, Inc.

9430 Key West Avenue, Suite 210
Rockville, MD 20850
http://www.adlyfe.com
12 Employees

SBIR Award Summary

Total Number of Awards 8
Total Value of Awards $3.15MM
First Award Date 01/15/04
Most Recent Award Date 11/22/06

Key Personnel

Last Name Name Awards Contact
Orser Dr. Cindy S. Orser 6
Ho Dr. David H. Ho 2 Message

8 Awards Won

Phase 2 SBIR

Agency: Office of the Secretary of Defense
Topic: OSD05-H05
Budget: 11/22/06 - 11/22/08

The prion disease process involves a conformational change in the prion protein that in turn can serve as the basis for an early detection, diagnostic, prognostic and screening assay. The Misfolded Protein Diagnostic (MPD) Assay detects infectivity in a crude sample through the use of labeled Pronucleon peptides that undergo conformational chan...

Phase 1 SBIR

Agency: Office of the Secretary of Defense
Topic: OSD05-H05
Budget: 12/21/05 - 12/21/06

Adlyfe Inc. has developed a highly sensitive fluorescence based test, called the Misfolded Protein Diagnostic (MPD) Assay, for the misfolded prion protein associated with infectivity. The femtomolar sensitivity of the test enables the presymptomatic detection in blood, which can be performed ante mortem in routine surveillance of live animals a...

Phase 2 SBIR

Agency: Office of the Secretary of Defense
Topic: OSD04-H17
Budget: 12/07/05 - 12/07/07

Blood loss due to uncontrolled hemorrhage is a major contribution to at least 90% of the combat death before reaching the field hospital. The ability to control heavy bleeding in the injured soldier is critical and will vastly improve the survival outcome in the theater. Furthermore, complications from uncontrolled bleeding in the microvasculatu...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/28/05 - 01/31/07

DESCRIPTION (provided by applicant): The major objective of the proposed project is to develop methodology that will allow fast and efficient detection of infectious prion proteins prior to the onset of clinical symptoms. This includes the detection of infectious prions in mortal products, early ante-mortem diagnostic of the prion diseases, a...

Phase 1 SBIR

Agency: Office of the Secretary of Defense
Topic: OSD04-H17
Budget: 01/11/05 - 01/11/06

The main goal of this proposal is to develop stabilized freeze-dried Yucatan pig platelets that will retain the majority of platelet biological properties, but can be stored in the dry state for years. These platelets will be incorporated into a hemostatic dressing that will control bleeding in the Yucatan pig wound and bone healing model. This ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/04 - 07/31/06

DESCRIPTION (provided by applicant): The major objective of the proposed project is to develop methodology that will allow fast and efficient detection of infectious prion proteins prior to the onset of clinical symptoms. This includes the detection of infectious prions in mortal products, early ante-mortem diagnostic of the prion diseases, a...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/04 - 04/30/05

DESCRIPTION (provided by applicant): The overall goal of this Phase I proposal is to determine the resiliency of platelets during the stabilization process to co-accumulate secondary compounds to enhance their wound healing attributes. This work is based on the extensive documentation of pooled secretion of growth factors from platelets for he...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 01/15/04 - 07/31/04

DESCRIPTION (provided by applicant): The major objective of the proposed project is to develop methodology that will allow fast and efficient detection of infectious prion proteins prior to the onset of clinical symptoms. This includes the detection of infectious prions in mortal products, early ante-mortem diagnostic of the prion diseases, a...