Alliance Pharmaceutical Corporation

San Diego, CA 92121

SBIR Award Summary

Total Number of Awards 5
Total Value of Awards $290K
First Award Date 06/01/98
Most Recent Award Date 09/01/00

Key Personnel

Last Name Name Awards Contact
Woods Catherine Woods 3
Casares Sofia Casares 1
Brumeanu Teodor-Doru Brumeanu Brumeanu 1

5 Awards Won

Phase 1 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/00 - 08/31/01

Our preliminary investigations have demonstrated that delivery of self peptide on genetically engineered immunoglobulin (Ig) vehicles increases peptide presentation to T cells by 100-1000 fold relative to free peptides. Furthermore, intraperitoneal injection of the self peptide-Ig chimera into mice with ongoing experimental allergic encephalomye...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 05/01/00 - 04/30/01

DESCRIPTION: (Adapted from the applicant's abstract): Insulin-dependent diabetes mellitus (IDDM, diabetes type I) is a chronic autoimmune disease resulting from T-cell mediated destruction of pancreatic beta-cells. The role of autoreactive Th1 cell subset in IDDM pathogenesis has been widely demonst...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 03/15/00 - 02/28/01

Helicobacter infection is widespread and has been shown to be a major causative agent for gastric carcinoma. Current therapies involve combination therapy including antibiotics but since the bacterium resides in the gastric mucus, antibiotic presentation is inefficient. A vehicle for topical administration of antibiotics directly to t...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/98 - 08/31/99

DESCRIPTION: (Adapted from the applicant's abstract) Conventional influenza viral vaccines show poor efficacy in infants and young children due to the immaturity of the immune system, as well as the inherent limited immunogenicity and inability to stimulate cell-mediated immunity of the inactivated viru...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 06/01/98 - 05/31/99

DESCRIPTION (Adapted from the applicant's abstract): H. pylori causes >90% of the cases of gastritis, peptic ulcer and stomach cancer. Current diagnostic methods are far from optimal: serologic tests cannot indicate whether H. pylori has been eradicated or determine bacterial antibiotic resistance a...