Ixion Biotechnology, Inc.

Alachua, FL 32615

SBIR Award Summary

Total Number of Awards 19
Total Value of Awards $4.12MM
First Award Date 09/30/96
Most Recent Award Date 07/03/06

Key Personnel

Last Name Name Awards Contact
Maddock Stephen W Maddock 1
Peck Ammon B Peck 2
Hatch Marguerite Hatch 3
Ramiya Vijayakumar K Ramiya 1
Yin Li Yin 1
Sidhu Harmeet Sidhu 7
Humphreys-Beher Michael G Humphreys-Beher 1
Bartelmez Stephen Hollis Bartelmez 1
Harris Robert G Harris 2

19 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/03/06 - 06/30/07

DESCRIPTION (provided by applicant): Type 1 diabetes (T1D) is an autoimmune disease that usually presents during the first 2 decades of life in which the pancreatic beta cells are destroyed by an aberrant immune response. Patients usually do not present with clinical disease until after the body's immune system has destroyed 90% or more of the t...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-99-84
Budget: 07/01/04 - 06/30/07

DESCRIPTION (provided by applicant): Use of indwelling catheters and stents long-term in the urinary tract is often limited due to the occurrence of encrustation and biofilm formation To date, there are no biomaterials used in the urinary tract that are completely biocompatible and capable of withstanding the effects of the urinary environment ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/03 - 08/31/06

DESCRIPTION (provided by applicant): Absence of Oxalobacter formigenes (Oxf) from the GI-tract is a risk factor for development of hyperoxaluria and calcium oxalate kidney stones. Recent data now indicate that patients with recurrent urolithiasis have a lower prevalence rate of Oxf in their stools than non-stone forming individuals. In addition,...

Phase 2 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/03 - 08/31/05

DESCRIPTION (provided by applicant): Sjogren's syndrome is a human autoimmune disease of the salivary and lacrimal glands that results in a debilitating xerostomia (dry mouth) and xerophthalmia (dry eyes). This syndrome may present as either a primary autoimmune disease or as a secondary autoimmune disease most often concomitant with other con...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-99-84
Budget: 07/01/03 - 06/30/04

DESCRIPTION (provided by applicant): Use of indwelling catheters and stents long-term in the urinary tract is often limited due to the occurrence of encrustation and biofilm formation To date, there are no biomaterials used in the urinary tract that are completely biocompatible and capable of withstanding the effects of the urinary environment ...

Phase 2 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 09/25/02 - 08/31/03

DESCRIPTION (provided by applicant): Sjogren's syndrome is a human autoimmune disease of the salivary and lacrimal glands that results in a debilitating xerostomia (dry mouth) and xerophthalmia (dry eyes). This syndrome may present as either a primary autoimmune disease or as a secondary autoimmune disease most often concomitant with other con...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/02 - 08/31/04

DESCRIPTION(provided by applicant): Calcium oxalate stone disease is a prevalent disease with limited preventative treatment options. Dietary oxalate makes an important contribution to urinary oxalate excretion and a strong body of evidence suggests it plays an important role in calcium oxalate stone format...

Phase 2 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/02 - 08/31/04

Approximately one million cases of stone disease are diagnosed in the United States every year and hyperoxaluria is considered to be a major risk factor. Our goal is to reduce the burden of oxalate excretion by the kidneys before the onset of renal failure caused by the oxalate-induced insults of hyperoxaluria, oxalate crystal deposition in tiss...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/02 - 08/31/03

DESCRIPTION (provided by applicant): Absence of Oxalobacter formigenes (Oxf) from the GI-tract is a risk factor for development of hyperoxaluria and calcium oxalate kidney stones. Recent data now indicate that patients with recurrent urolithiasis have a lower prevalence rate of Oxf in their stools than non-stone forming individuals. In addition,...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 05/15/02 - 11/30/03
PI: Li Yin

Type 1 diabetes is caused by the progressive ablation of insulin- producing pancreatic beta cells by autoreactive T cells. The resulting insulin insufficiency often leads to uncontrolled glucose excursions despite regular insulin replacement therapy. Such hyperglycemic, over a long period of time, results in debilitating secondary complications ...

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