Dyad Pharmaceutical Corporation

Columbia, MD 21046

SBIR Award Summary

Total Number of Awards 4
Total Value of Awards $0.0
First Award Date 05/01/93
Most Recent Award Date 08/01/95

Key Personnel

Last Name Name Awards Contact
Alul Rushdi Alul 1
Hoke Glenn D Hoke 1
Bhan Purshotam Bhan 2

4 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/95 - 07/31/96

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/94 - 07/31/95

The use of antisense oligonucleotides for regulation of gene expression has received widespread attention as a new class of potential chemotherapeutic agents. Many oligonucleotide analog structures have been studied for this purpose. There is presently no universally applicable oligonucleotide structure to serve as an antisense effector. The SBI...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/93 - 02/28/94

Endometrial hyperplasia (EH) is characterized by hyperproliferation of the endometrium. Women with EH are at increased risk for developing endometrial carcinoma, the most common malignant neoplasm of the urogenital tract in women. Unopposed estrogen or hyperestrogenism, which can arise from hormonal imbalances that occur during menopause, obesi...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 05/01/93 - 10/31/93

Antisense oligonucleotides are under intense investigation as novel therapeutics for sequence specific regulation of gene expression. We have designed and incorporated an internucleotidic linkage as part of an oligonucleotide structure that retains the base-recognition properties, aqueous solubility and achirality of natural deoxyoligonucleotid...