Control Delivery Systems, Inc.

Watertown, MA 02172

SBIR Award Summary

Total Number of Awards 15
Total Value of Awards $1.18MM
First Award Date 09/30/95
Most Recent Award Date 09/30/01

Key Personnel

Last Name Name Awards Contact
Smith Thomas J. Smith 8
Ashton Paul Ashton 4
Shimizu Robert W Shimizu 3

15 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/01 - 09/29/02

DESCRIPTION: The goal of this fast-track phase I / II proposal is to reduce or eliminate blindness due to rejection of corneal transplants in high risk, penetrating keratoplasty. The specific aim of the phase I project is to test the efficacy of a cyclosporine implant in a rabbit model of corneal graft ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/00 - 09/29/01

DESCRIPTION: The goal of this fast-track phase I / II proposal is to reduce or eliminate blindness due to rejection of corneal transplants in high risk, penetrating keratoplasty. The specific aim of the phase I project is to test the efficacy of a cyclosporine implant in a rabbit model of corneal graft ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/00 - 08/31/01

Phase 2 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/00 - 08/31/01

The broad long term goal of this research is to reduce or eliminate blindness due to uveitis. In phase I of this SBIR we developed 3 year intraocular cyclosporine devices. We prepared high and low dose devices, validated sterilization procedures, and began release rate testing in vivo. Preclinical efficacy and toxicity data has enabled a Phas...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/99 - 03/31/00

The broad long-term goal of this research is to reduce or eliminate blindness due to choroidal neovascular membrane formation (CNVM) in Age-Related Macular Degeneration (ARMD). Up to 87 percent of eyes with CRNV present with "ill-defined" lesions. No beneficial treatment for this form of choroidal neovascularization has been established. Hist...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/99 - 08/31/00

Phase 2 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 09/07/99 - 08/31/00

The broad long term goal of this research is to reduce or eliminate blindness due to uveitis. In phase I of this SBIR we developed 3 year intraocular cyclosporine devices. We prepared high and low dose devices, validated sterilization procedures, and began release rate testing in vivo. Preclinical efficacy and toxicity data has enabled a Phas...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/98 - 09/29/99

DESCRIPTION: The goal of this fast-track phase I / II proposal is to reduce or eliminate blindness due to rejection of corneal transplants in high risk, penetrating keratoplasty. The specific aim of the phase I project is to test the efficacy of a cyclosporine implant in a rabbit model of corneal graft ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/98 - 07/31/00

The broad long term goal of this research is to reduce or eliminate the blindness in AIDS patients caused by CMV retinitis, the principal cause of blindness in AIDS. We have developed a sustained release intravitreal delivery system delivering 1ug/hr of ganciclovir over approximately 8 months which has recent...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 05/11/98 - 11/10/98

DESCRIPTION: The purpose of the proposed study is to use a polymer based sustained release antiviral drug delivery system that can be implanted in patients for anti-HIV therapy. Such a device has been developed for treatment of CMV retinitis and was approved by the FDA. The long term goal is to prevent ver...

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