Diversa Corporation

4955 Directors Place
San Diego, CA 92121

SBIR Award Summary

Total Number of Awards 27
Total Value of Awards $4.41MM
First Award Date 09/30/96
Most Recent Award Date 04/01/04

Key Personnel

Last Name Name Awards Contact
Warren Patric V Warren 1
Stein Jeffrey L Stein 2
Kretz Keith A Kretz 3
Keller Martin Keller 3
Robertson Dan E Robertson 2
Bibb Mervyn J Bibb 1
Nunn David N Nunn 1
Lafferty W Michael Lafferty 2
Stege Justin T Stege 2
Xu Karen D Xu 2
Zhao Lishan Zhao 1
Trefzer Axel Trefzer 1
Green Brian D Green 1
Barton Nelson Barton 2 Message
Blum David L. Blum 3 Message
Short Jay M. Short 3 Message
Wood Ray Wood 1 Message

27 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/04 - 12/31/04

DESCRIPTION (provided by applicant): Polyketides are a large group of important bioactive compounds that include many anti-microbial agents. Most bioactive polyketides of microbial origin are made by actinomycetes, which are high GC Gram-positive bacteria frequenting both terrestrial and marine environments. Genes dedicated to the synthesis of ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 02/01/04 - 12/15/04

DESCRIPTION (provided by applicant): This effort is aimed at the development of an advanced screening platform that overcomes the functional and throughput limitations of conventional screening methodologies for the discovery of new enzymes, protein therapeutics, and small molecule drugs. We propose to further develop the million-well GigaMatrix...

Phase 2 SBIR

Agency: National Science Foundation
Topic: 2004
Budget: 01/01/04 - 12/31/04

This Small Business Innovation Research Phase II project will develop a powerful enzyme / biocide formulation for industrial water treatment. The research concept targets enzyme-facilitated diffusion of biocide for maximum biofilm control efficacy and provides a resultant low cost product with lowered environmental load. Proprietary gene evoluti...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 05/01/03 - 04/30/04

DESCRIPTION (provided by applicant): The ultimate goal of this project is to develop a biosynthetic route to produce the insecticide emamectin from the natural product avermectin. Emamectin is a broad spectrum insecticide with low environmental impact that is not widely used due to the high cost of the current chemical production process. A more...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 02/01/03 - 07/30/03

DESCRIPTION (provided by applicant): The goal of this program is to build a powerful and flexible platform for the biosynthesis of novel glycosylated natural products for pharmaceutical and agrochemical uses. Natural products are a proven source of valuable leads in pharmaceutical drug development. The platform will exploit the substrate flex...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 02/01/03 - 07/31/03

DESCRIPTION (provided by applicant): Enantiopure epoxides and vicinal diols are valuable, but difficult to synthesize building blocks for fine chemical and numerous pharmaceuticals. Epoxide hydrolases, which catalyze the hydrolysis of racemic epoxides to generate both the corresponding diols and the un-reacted epoxides, are promising biocatal...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-01-91
Budget: 02/01/03 - 07/31/04

DESCRIPTION (provided by applicant) Polyketides are a large group of important bioactive compounds that include many anti-tumor agents. Most known bioactive polyketides of microbial origin are made by actinomycetes, which are high GC Gram-positive bacteria frequenting both terrestrial and marine environments. Genes dedicated to the synthesis o...

Phase 2 SBIR

Agency: Department of Energy
Topic: 2003
Budget: 01/01/03 - 12/31/03

70920S02-II There is a need for more cost effective enzyme systems for the conversion of lignocellulosic biomass to fermentable sugars for the production of ethanol. Cellobiohydrolase could be an effective enzyme for the efficient breakdown of lignocellulose, but little effort has been expended on improving the technical efficacy of this cla...

Phase 1 SBIR

Agency: Department of Energy
Topic: 2003
Budget: 01/01/03 - 12/31/03

70920S02-II There is a need for more cost effective enzyme systems for the conversion of lignocellulosic biomass to fermentable sugars for the production of ethanol. Cellobiohydrolase could be an effective enzyme for the efficient breakdown of lignocellulose, but little effort has been expended on improving the technical efficacy of this cla...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/15/02 - 03/14/03

DESCRIPTION (provided by applicant): Methods for the rapid chromosomal evolution of bacterial or eukaryotic organisms have recently proven to be invaluable for the purpose of generating hosts for protein expression, small molecule production, fermentative processes and assay development. Unfortunately, most of these methods have a number of dra...

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