Third Wave Technologies, Inc.

THIRD WAVE TECHNOLOGIES, INC., 506 S ROSA RD
Madison, WI 53719

SBIR Award Summary

Total Number of Awards 22
Total Value of Awards $3.42MM
First Award Date 04/01/93
Most Recent Award Date 09/01/04

Key Personnel

Last Name Name Awards Contact
Olive D Michael Olive 1
Fors Lance Fors 3
Neri Bruce P Neri 2
Kwiatkowski Robert W Kwiatkowski 6
Brow Mary A Brow 4
Olson Marilyn C Olson 1
Ip Hon S Ip 2
Domanico Michael J Domanico 1
Ann D Brow Ms. Mary Ann D Brow 2

22 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/04 - 04/30/06

DESCRIPTION (provided by applicant): The objectives of Phase II are to develop, validate, and commercialize a tool for detecting genotypes affecting patient care and safety during the perioperative interval (before, during, and immediately following surgery). Despite publications describing genetic risk factors, genetic screening is not performe...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/08/03 - 08/31/04

DESCRIPTION (provided by applicant): The objectives of Phase II are to develop, validate, and commercialize a tool for detecting genotypes affecting patient care and safety during the perioperative interval (before, during, and immediately following surgery). Despite publications describing genetic risk factors, genetic screening is not performe...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/01/02 - 12/31/03

DESCRIPTION (provided by applicant): The goal of this project is to create a high throughput, sensitive, quantitative and cost-effective platform for measuring gene expression in response to natural compounds derived from foods -nutraceuticals. This technology, the RNA InvaderTM assay, offers highly sensitive detection of mRNA messages directly...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/25/01 - 03/24/02

The goal of this project over Phase I is to create and test the analytical validity of novel Invader mutation detection assays designed for applications specific to surgery and anesthesia. Invader technology, based on a highly specific enzyme-substrate reaction, enables direct analysis of genomic DNA without prior amplification, conferring advan...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/01 - 03/31/03

The objective of this proposal is to create a high-throughput, low-cost system for predicting the success of antiviral treatment of individuals infected by Human Immunodeficiency Virus (HIV). The core of our approach is the Invader assay, a linear signal amplification method suitable for point mutation detection, even of low-level minority allel...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/01 - 03/31/02
PI: Hon S Ip

The goal of this Phase II Proposal is the development of a simple, cost- effective, and high-throughput method for detecting RNA directly and quantitatively. The advent of genome-wide sequencing projects and expression array analysis has led to an unprecedented demand for an accurate method to measure specific gene expression that can accommoda...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/00 - 03/31/01

The objective of this proposal is to create a high-throughput, low-cost system for predicting the success of antiviral treatment of individuals infected by Human Immunodeficiency Virus (HIV). The core of our approach is the Invader assay, a linear signal amplification method suitable for point mutation detection, even of low-level minority allel...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/00 - 03/31/01
PI: Hon S Ip

The goal of this Phase II Proposal is the development of a simple, cost- effective, and high-throughput method for detecting RNA directly and quantitatively. The advent of genome-wide sequencing projects and expression array analysis has led to an unprecedented demand for an accurate method to measure specific gene expression that can accommoda...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/99 - 01/31/00

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PAR-98-066
Budget: 03/01/99 - 02/29/00

The goal of this project, over Phases I and II, is to create a new, accurate and quantitative platform for massively parallel, ultra high throughput screening of SNPs, mutations, and gene expression on solid supports, e.g. chips. This platform, based on our novel, linear signal amplification technology, the Invader assay, will immediately impact...

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