Pharmagenics, Inc.

Allendale, NJ 07401

SBIR Award Summary

Total Number of Awards 2
Total Value of Awards $0.0
First Award Date 08/01/93
Most Recent Award Date 05/12/94

Key Personnel

Last Name Name Awards Contact
Stoller Timothy J Stoller 1
Beaudry Gary A Beaudry 1

2 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 05/12/94 - 05/11/95

DESCRIPTION (Adapted from applicant's abstract): Loss of p53 tumor suppressor gene function occurs in a majority of human cancers. Inactivation of p53 may be a crucial step in tumor development. Certain tumors and tumor cell lines contain an amplified MDM2 gene. MDM2 protein binds p53 protein in vitro and in vivo and can block the transact...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/93 - 01/31/94

While the cause of systemic lupus erythematosus (SLE) remains unknown, the role of anti-DNA antibodies in the progression of SLE has been recognized for over three decades. Specific determinants on DNA recognized by pathogenic anti-DNA antibodies remain to be elucidated. Difficulty in identifying these elements stems from antibody heterogeneit...