Fermalogic, Inc.

Chicago, IL 60612

SBIR Award Summary

Total Number of Awards 24
Total Value of Awards $4.91MM
First Award Date 04/01/93
Most Recent Award Date 09/01/09

Key Personnel

Last Name Name Awards Contact
Weber J. Mark Weber 21
Reeves Andrew R Reeves 3

24 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-08-050
Budget: 09/01/09 - 08/31/10

DESCRIPTION (provided by applicant): Knowledge of amino acid metabolism is critical to human health and has significant industrial applications as well. This study proposes to develop a coproduct method for the production of L-lysine, an essential amino acid of great economic and industrial importance. If successful, the L-lysine produced as a r...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-07-80
Budget: 09/01/08 - 08/31/10

DESCRIPTION (provided by applicant): Industrial metabolic engineering is a method for performing strain improvement in industrial microorganisms by harnessing the power of random in vitro transposition mutagenesis. The organisms we aim to improve in this study are the actinomycetes, a group of soil bacteria that are best known for their ability ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-20
Budget: 09/15/07 - 09/14/09

DESCRIPTION (provided by applicant): Fermalogic recently discovered that the key erythromycin precursor, methylmalonyl- CoA, is the limiting factor for improved erythromycin production. As such, the methylmalonyl-CoA metabolic node has become a focal point for strain improvement strategies. The main goals of this study are to identify key enzyme...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-20
Budget: 02/15/07 - 02/14/08

DESCRIPTION (provided by applicant): A type of metabolic engineering described in this proposal, and referred to as "industrial" metabolic engineering, is a method for performing strain improvement in industrial microorganisms by harnessing the power of in vitro transposition mutagenesis. The industrial microorganisms of interest to this study a...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/05 - 08/31/06

DESCRIPTION (provided by applicant): Strain improvement of industrial microorganisms is required at both the clinical testing stage and commercialization stage of drug development. Although strain improvement plays an enormous economic role in reducing the costs of pharmaceutical manufacturing, this role is generally unrecognized by the public,...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/05 - 03/31/07

DESCRIPTION (provided by applicant): Rapamycin (sirolimus) has recently been approved for clinical use in transplantation medicine and improved derivatives are already under development. Rapamycin also has potential as an anti-cancer therapeutic, therefore the market for this compound is expanding rapidly. The current problem is that the rapamy...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/04 - 08/31/05

DESCRIPTION (provided by applicant): Strain improvement of industrial microorganisms is required at both the clinical testing stage and commercialization stage of drug development. Although strain improvement plays an enormous economic role in reducing the costs of pharmaceutical manufacturing, this role is generally unrecognized by the public,...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/04 - 08/31/06

DESCRIPTION (provided by applicant): Commercial applications for soy isoflavones have grown significantly in recent years. Isoflavones are used in health foods and as nutritional supplements. More recently they are being investigated as antioxidants, protecting skin from UV damage when taken orally or used topically. More importantly, isoflavone...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/03 - 08/31/04

DESCRIPTION (provided by applicant): Commercial applications for soy isoflavones have grown significantly in recent years. Isoflavones are used in health foods and as nutritional supplements. More recently they are being investigated as antioxidants, protecting skin from UV damage when taken orally or used topically. More importantly, isoflavone...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 05/01/03 - 04/30/04

DESCRIPTION (provided by applicant): The objective of the proposed study is to generate novel macrolide and ketolide structures that may be useful as antibiotics themselves, or as chemical intermediates in the generation of new semi-synthetic antibiotics. Macrolides are effective in the treatment of respirtory infections. The new ketolide der...

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