Targeted Genetics Corporation

Seattle, WA 98101

SBIR Award Summary

Total Number of Awards 5
Total Value of Awards $0.0
First Award Date 02/01/95
Most Recent Award Date 09/01/97

Key Personnel

Last Name Name Awards Contact
Skalka Anna Marie Skalka 1
Reynolds Thomas C. Reynolds 3
Daifuku Richard Daifuku 1

5 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/97 - 08/31/98

The proposed research is intended to develop a large scale cell process and purification system for the production of recombinant AAV-CFTR vector. A suspension adapted packaging cell line will be constructed. This cell line will be used to develop a large scale batch suspension process utilizing a tem...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/11/97 - 09/30/98

HER-2/neu is an onocogene which is overexpressed in 30% of patients with ovarian and breast cancer. Its overexpression has a direct correlation with poor long term survival. Researchers from M.D. Anderson Cancer Center observed that the E1A gene from adenovirus type 5 functions as a tumor suppressor gene for tum...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/96 - 09/29/98

The long term objective of this project is to develop a technology which could significantly improve the efficacy of stable gene transfer to human cells. The technology is designed to exploit the biochemical activities of retrovirus-encoded integrase (IN) within a non-viral gene delivery system. In vitro, IN a...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/96 - 08/31/97

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 02/01/95 - 07/31/95

The long term objective of this project is to develop a scalable GMP manufacturing process for the production of adeno-associated virus (AAV) vectors for the treatment of cystic fibrosis. AAV-CFTR vector constructs will be introduced into a variety of cell lines and evaluated for their ability to produce vector particles following addition ...