Invitrogen Corporation

Carlsbad, CA 92008

SBIR Award Summary

Total Number of Awards 24
Total Value of Awards $1.09MM
First Award Date 09/01/94
Most Recent Award Date 05/01/00

Key Personnel

Last Name Name Awards Contact
Bennett Robert P Bennett 4
Hoeffler James P Hoeffler 9
Higgins David Higgins 1
Russell Marijane R Russell 3
Chesnut Jonathan D Chesnut 2
Madden Knut R Madden 1
Kusser Wolfgang C Kusser 1
Heyman John A Heyman 2
Carrino John J Carrino 1

24 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 05/01/00 - 04/30/01

This proposal outlines the development of VP22 as a delivery vehicle for protein and DNA molecules to cells in culture. The Phase I proposal demonstrated the power of protein-mediated delivery by expressing and purifying protein fusions with the Antennapedia peptide from E. coli. These fusion proteins were translocated across biological membrane...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: RFA-CA-98-04
Budget: 04/01/00 - 03/31/01

DESCRIPTION: (Applicant's Description) Gene cloning and expression are enabling technologies linking genomics to functional genomics. Together, they allow scientists to convent the genetic information from a genome into proteins, the functional units of life. Invitrogen's cloning and expression ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 01/01/00 - 12/31/00

DESCRIPTION: (Adapted from the applicant's abstract) This Phase II SBIR application discusses the rationale and approach for further development of the SMART reagent system. Phase I developed a modified two-hybrid system in yeast for isolating single-chain antibodies (sFv's) with high affinity for desired antigen...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 05/14/99 - 04/30/00

This proposal outlines the development of VP22 as a delivery vehicle for protein and DNA molecules to cells in culture. The Phase I proposal demonstrated the power of protein-mediated delivery by expressing and purifying protein fusions with the Antennapedia peptide from E. coli. These fusion proteins were translocated across biological membrane...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/15/99 - 12/31/99

DESCRIPTION: (Adapted from the applicant's abstract) This Phase II SBIR application discusses the rationale and approach for further development of the SMART reagent system. Phase I developed a modified two-hybrid system in yeast for isolating single-chain antibodies (sFv's) with high affinity for desired antigen...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: RFA-CA-98-04
Budget: 04/01/99 - 03/31/00

DESCRIPTION: (Applicant's Description) Gene cloning and expression are enabling technologies linking genomics to functional genomics. Together, they allow scientists to convent the genetic information from a genome into proteins, the functional units of life. Invitrogen's cloning and expression ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: RFA-CA-98-04
Budget: 04/01/99 - 03/31/00

DESCRIPTION: (Applicant's Description) Gene cloning and expression are enabling technologies linking genomics to functional genomics. Together, they allow scientists to convent the genetic information from a genome into proteins, the functional units of life. Invitrogen's cloning and expression ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/99 - 09/30/99

DESCRIPTION: (Adapted from the investigator's abstract) This proposal outlines plans to extend the applicability of the yeast display system, which was developed recently at the University of Illinois for studying protein-protein and protein-ligand interactions. The technology was invented by Dr. K. D. Wittrup...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/99 - 09/30/99

The elucidation of cell signaling pathways and protein oligomerization mechanisms will lead to a better understanding of disease as well as cellular homeostasis. Since essentially all biochemical interactions involve protein ligand interactions, the development of efficient methods of detecting these interactions is critical. The novel phage dis...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 01/01/99 - 06/30/99

In this proposal we will develop methods to substantially increase the utility of dye-labeled terminator sequencing technology, and reduce the cost, by developing fluorescent dyes and modified dideoxynucleotide chain terminators. The proposed combination of a versatile acceptor nucleotide and compatible label pr...

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