Omnigene Diagnostics, Inc.

Cambridge, MA 02142

SBIR Award Summary

Total Number of Awards 4
Total Value of Awards $0.0
First Award Date 08/01/91
Most Recent Award Date 06/01/96

Key Personnel

Last Name Name Awards Contact
Panicali Dennis L Panicali 1
Hill David E. Hill 1
Young Elihu M Young 2

4 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/01/96 - 05/31/97

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/01/96 - 03/29/97

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/20/93 - 10/31/93

Mutations in the APC gene appear to be crucial for adenoma formation in inherited Familial Adenomatous Polyposis (FAP) and in the early stages of colorectal cancer. Analysis of the APC gene has identified mutations in germ line DNA of FAP patients. Over 90% of the mutations interrupt the reading frame suggesting the presence of a truncated APC...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/91 - 12/04/91

The Phase I studies established the feasibility of using molecular approaches to derive from the NYCBH vaccine strain, stable attenuated mutants of unaltered immune efficacy. In this Phase II proposal selected mutants generated in the virulent NYCBH-IH isolate will be studied to determine their virulence parameters and immune protective capacit...