Chaotic Dynamical Systems

Guilford, CT 06437

SBIR Award Summary

Total Number of Awards 9
Total Value of Awards $526K
First Award Date 06/12/90
Most Recent Award Date 08/07/02

Key Personnel

Last Name Name Awards Contact
Pincus Steven M Pincus 9

9 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/07/02 - 01/31/03

DESCRIPTION (provided by applicant): The primary objective is to determine the relationship between clinical growth in pubertal girls and boys and shifts in the irregularity of underlying growth hormone (GH) secretory patterns. Novel clarifications of this time-evolution could be significant in determining the proper timing of hormone replaceme...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 05/01/01 - 04/30/02

The primary objective is to determine minimal sampling frequencies and study durations required to significantly differentiate hormonal secretory patterns between clinically distinct cohorts, via Approximate entropy (ApEn) and cross-ApEn, quantifications of sequential irregularity and two-variable asynchrony, respectively, developed by the princ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 05/15/00 - 04/30/01

The primary objective is to determine minimal sampling frequencies and study durations required to significantly differentiate hormonal secretory patterns between clinically distinct cohorts, via Approximate entropy (ApEn) and cross-ApEn, quantifications of sequential irregularity and two-variable asynchrony, respectively, developed by the princ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/31/98 - 07/31/99

DESCRIPTION: The primary objective is to determine minimal sampling frequencies and study duration required to significantly differentiate hormonal secretory patterns between clinically distinct cohorts, via approximate entropy (ApEn), a quantification of sequential irregularity developed by the princi...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 03/15/96 - 06/14/97

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/94 - 04/30/96

The principal investigator has developed a mathematical statistic, ApEn, to analyze time-series data. The primary objective of this proposal is to examine the potential use of ApEn as a biomarker of aging, to predict adverse consequences of autonomic dysfunction, such as hypotension and syncope, and to evaluat...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/93 - 07/31/94

The principal investigator has developed a mathematical statistic, ApEn, to analyze time-series data. The primary objective of this proposal is to examine the potential use of ApEn as a biomarker of aging, to predict adverse consequences of autonomic dysfunction, such as hypotension and syncope, and to evaluate such interventions as exercise an...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/91 - 09/30/91

The principal investigator has developed a mathematical statistic, ApEn, to analyze time-series data. The long term objective of this proposal is to examine the potential use of ApEn as a biomarker of aging, to predict adverse consequences of autonomic dysfunction, such as hypotension and syncope, and to evaluate such interventions as exercise ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/12/90 - 12/11/90

The principal investigator has developed a novel non-invasive mathematical approach and formula, ApEn, based on the science of Chaos, to analyze heartbeat data. The long-term objective of this proposal is to examine the potential use of ApEn to identify those at risk for SIDS. It is anticipated that ApEn will provide diagnostic and predictive ...