Oscient Pharmaceuticals Corporation

Waltham, MA 02453

SBIR Award Summary

Total Number of Awards 35
Total Value of Awards $2.23MM
First Award Date 01/15/91
Most Recent Award Date 06/15/04

Key Personnel

Last Name Name Awards Contact
Mao Jen-I I. Mao 8
Moir Donald T Moir 5
Call Katherine M Call 3
Keith Tim P. Keith 2
Doucette-Stamm Lynn Doucette-Stamm 2
Little Randall D Little 1
Guarente Barbara Guarente 1
Lundstrom Ronald S Lundstrom 1
Carulli John P Carulli 2
Ling Losee Lucy Ling 1
Artinger Michael A Artinger 1
Smith Douglas R Smith 3
Del Mastro Richard G Del Mastro 4
Opperman Timothy J Opperman 1

35 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-00-18
Budget: 06/15/04 - 09/30/04

DESCRIPTION (provided by applicant): Our goal is to accelerate the rate of discovery of novel therapeutic agents by rapidly assigning function to genes with no experimental functional data (NEFD) and organizing them within Protein Interaction Network (PIN) maps. This will facilitate the identification of novel candidate drug targets in disease-a...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-02-10
Budget: 02/01/04 - 08/31/04

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-00-18
Budget: 08/01/03 - 01/31/04

DESCRIPTION (provided by applicant): Our goal is to accelerate the rate of discovery of novel therapeutic agents by rapidly assigning function to genes with no experimental functional data (NEFD) and organizing them within Protein Interaction Network (PIN) maps. This will facilitate the identification of novel candidate drug targets in disease-a...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-02-10
Budget: 08/01/03 - 01/31/04

DESCRIPTION (provided by applicant): ADAM33 has been identified as an Asthma susceptibility gene. A set of disease-associated single nucleotide polymorphisms (SNPs) have been identified that confer no obvious perturbation on the expressed transcript or the protein that it encodes. We hypothesize that in asthma and other complex diseases, associa...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/03 - 10/31/03

DESCRIPTION (provided by investigator): Biofilms are surface attached bacterial communities encased in a hydrated matrix of exopolysaccharide. In the body, infecting bacteria form biofilms on medical implants, such as indwelling catheters. In this biofilm mode of growth, they are resistant to antibiotics and attack by the body's immune system. ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PAS-02-149
Budget: 07/15/03 - 10/31/03

DESCRIPTION (provided by investigator): Burkholderia pseudomallei is a bioterrorist threat. With the best current therapies, lethality is typically as high as 40%. The overall goal of this application is the development of new drugs against this organism. In Phase I, we will exploit the high sequence similarity between B. pseudomallei and its l...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 03/01/01 - 02/28/02

The goal of this project is to develop new techniques for Ultra High Throughput Sequencing to enable rapid, low cost pharmacogenetic analysis of genes involved in cancer susceptibility, progression, and treatment. Overall, a 5-fold reduction in-costs will be achieved compared to "l/4x" ABI sequencing reactions. Part of this cost reduction will b...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/19/00 - 02/28/01

The goal of this project is to develop new techniques for Ultra High Throughput Sequencing to enable rapid, low cost pharmacogenetic analysis of genes involved in cancer susceptibility, progression, and treatment. Overall, a 5-fold reduction in-costs will be achieved compared to "l/4x" ABI sequencing reactions. Part of this cost reduction will b...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 03/01/99 - 10/31/99

The goal of this project is to develop new techniques for Ultra High Throughput PCR-based sequencing to enable rapid, low cost pharmacogenetic analysis of genes involved in cancer susceptibility, progression, and treatment. Overall, a 10x reduction in operating costs will be achieved compar...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/97 - 08/31/00

Pax-6 is an essential nervous system transcription factor that is involved in basic pattern formation during development, as well as in several inherited disorders. The goal of this research is to clone pax-6 regulated promoters from the human genome, and to identify genes associated with the pro...

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