Enzon Labs

Gaithersburg, MD 20877

SBIR Award Summary

Total Number of Awards 3
Total Value of Awards $0.0
First Award Date 01/01/90
Most Recent Award Date 07/01/90

Key Personnel

Last Name Name Awards Contact
Filpula David R Filpula 2
Whitlow Marc D Whitlow 1

3 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/01/90 - 12/31/91

The objective of the proposed research is to engineer the structure of anti-fluorescein (anti-FL) single chain antigen binding (SCA TM) proteins for improved stability and modification of binding affinity and specificity. In Phase I, Genex developed an SCA protein against the hapten fluorescein because the binding of this antigen can be easily ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 05/01/90 - 03/31/91

The objective of this research program is to use protein engineering to generate staphylococcal Protein A variant which possess strong binding affinity for immunoglobulin species which are not significantly bound by natural Protein A. The experimental program will involve a sequential series of experiments of increasing levels of difficulty enco...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 01/01/90 - 09/30/90

A Single-Chain Antibody (SCA) protein with catalytic activity will be prepared. The SCA protein will be designed form the variable region sequences of one of two antibodies found to have lipase activity, either 2H6 ro 21H3. A gene to synthesize this protein will be constructed and the protein will be expressed in E. coli. The protein will be ...