Institute of Molecular Biology, Inc.

Worcester, MA 01605

SBIR Award Summary

Total Number of Awards 6
Total Value of Awards $0.0
First Award Date 02/01/89
Most Recent Award Date 04/20/94

Key Personnel

Last Name Name Awards Contact
Lynch Samuel E Lynch 5
Finkelman Richard D Finkelman 1

6 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/20/94 - 10/19/94

Postmenopausal (estrogen deficiency-induced) osteoporosis is a major public health problem predisposing to fracture and resulting in significant morbidity and mortality. Current therapies can stabilize bone mass but can not repair or restore lost bone. Thus, a critical need exists to improve therapeutics for the treatment of osteoporosis. Growth...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/15/94 - 10/14/94

Diabetic foot, venous stasis and pressure ulcers are examples of chronic non healing wounds that are refractory to standard therapy and represent a major health care problem especially for the increasing elderly population. Polypeptide growth factors are a class of biological mediators which have been proposed as possible vulnerary agents. The...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 02/01/94 - 07/31/94

Preliminary data have shown that a combination of insulin-like growth factor-I (IGF-I) and platelet-derived growth factor (PDGF) acts synergistically to enhance the rate and quality of rats sciatic nerve regeneration. This project will investigate the optimal clinically acceptable carrier of IGF-I and PDGF, in combination, to enhance the regene...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/01/93 - 11/30/93

Diabetic foot, venous stasis and pressure ulcers are examples of chronic non healing wounds, that are refractory to standard therapy and represent a major health care problem especially for the increasing elderly population. Polypeptide growth factors are a class of biological mediators which have been proposed as possible vulnerary agents. Th...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/01/91 - 05/31/92

Periodontal disease causes the destruction of the supporting structures of teeth including alveolar bone, functioning tooth root surface cementum and periodontal ligament. At present there is little that can be done to predictably enhance osteoneogenesis and regeneration of the periodontal structures. During Phase I we have shown that the comb...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 02/01/89 - 07/31/89