Baker Norton Pharmaceuticals, Inc.

Miami, FL 33178

SBIR Award Summary

Total Number of Awards 3
Total Value of Awards $0.0
First Award Date 06/01/89
Most Recent Award Date 09/01/91

Key Personnel

Last Name Name Awards Contact
Hahn Elliot F Hahn 3

3 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/91 - 08/31/92

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/90 - 08/31/91

Phase I results have demonstrated the feasibility of synthesizing phosphate-linked dimers of specific dideoxynucleosides which exhibit anti- HIV activity. The dimers showed enhanced activity and less cytotoxicity in in vitro assays when compared to combinations of the parent drugs. The results suggest that lower amounts of dimer may be require...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/01/89 - 11/30/89

A series of compounds which are either homo or heterodimers of specific dideoxynucleosides have been synthesized. In various assays the phosphate- linked dimers of such antiviral monomeric dideoxynucleosides possess greater activity than the combined activity of the dideoxynucleosides administered alone. Preliminary pharmacokinetic data obtain...