Specialty Laboratories, Inc.

Santa Monica, CA 90404

SBIR Award Summary

Total Number of Awards 9
Total Value of Awards $0.0
First Award Date 08/01/87
Most Recent Award Date 09/01/97

Key Personnel

Last Name Name Awards Contact
Peter James B Peter 1
Denis Kathleen A Denis 1
Mullis Kary B Mullis 1
Alosachie Iyad J Alosachie 3
Bean Pamela Bean 1
Faller Larry D Faller 1
Sevall J Sanders Sevall 1

9 Awards Won

Phase 1 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/97 - 08/31/98

DESCRIPTION (Adapted from the applicant's abstract): This is a proposal to improve the breath test for the detection of Helicobacter pylori in order to facilitate the diagnosis of gastrointestinal infections (ulcers, gastritis) associated with this microbe. As the NIH Consensus Panel did not recommend routine t...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/97 - 02/28/98

DESCRIPTION: Emerging and re-emerging bacterial diseases threaten the health of the U.S. population and molecular microbiological techniques afford the opportunity for efficient and cost-effective identification of these organisms. Much of the previous work has relied upon unique primers specific to each organi...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/01/95 - 12/31/95

The magnitude of alcohol related problems in the United States is staggering, with 20-40% of all hospital beds being occupied by patients with alcohol-induced and/or related problems. The fiscal costs are estimated at greater than $100 billion annually. Currently, carbohydrate- deficient transferrin (...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/08/94 - 07/31/95

In the Phase I of the SBIR, we developed antibody probes to synthetic peptides deduced from the sequence of beta2AR. Additionally, we expressed the complete sequence of beta2AR in three expression vectors: pEXB beta- galactosidase fusion protein), pINHB (a "secretory" vector) and in human kidney cell line (293). The receptor expression and antib...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/15/93 - 07/31/94

In the Phase I of the SBIR, we developed antibody probes to synthetic peptides deduced from the sequence of beta2AR. Additionally, we expressed the complete sequence of beta2AR in three expression vectors: pEXB beta- galactosidase fusion protein), pINHB (a "secretory" vector) and in human kidney cell line (293). The receptor expression and antib...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/91 - 01/31/92

DESCRIPTION (Adapted from applicant's abstract): The overall goal of this work is to develop a rapid DNA extraction protocol that can be applied to human body fluids, sputa and stool samples. The basis of the isolation procedure is to solubilize the clinical specimen with the strong detergent sodium dodecylsulfate (SDS). The solubilization re...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/01/91 - 12/31/91

DESCRIPTION: (Adapted from the applicant's abstract) The overall goal of this work is to develop an adoptive immunization scheme using SCID mice reconstituted with human peripheral blood lymphocytes to generate antigen-specific human MAbs, SCID mice will be pretreated with cytotoxic agents to give improved levels of early human cell reconstitut...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 02/01/91 - 07/31/91

DESCRIPTION: (Adapted from the Applicant's Abstract) The beta-2 adrenergic receptor is an important neurotransmitter receptor, which is involved in the regulation of multiple cellular systems. Dysfunction of the receptor is involved in several pathological states including asthma, hypertension, myocarditis and dilated cardiomyopathy. Measurem...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/87 - 01/31/88

Successful organ transplantation requires sustained immunosuppression. Currently, immunosuppressive treatment for cardiac allograft recipients is determined empirically. We have developed a sensitive and accurate technique to predict or confirm organ rejection and to discover if immunosuppressive treatment has modulated the immune response. F...