Urocor, Inc.

Oklahoma City, OK 73104

SBIR Award Summary

Total Number of Awards 9
Total Value of Awards $399K
First Award Date 09/01/92
Most Recent Award Date 06/01/01

Key Personnel

Last Name Name Awards Contact
Veltri Robert W Veltri 6
Ralph David A Ralph 1
Prescott James L Prescott 1
An Gang An 1

9 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/01/01 - 11/30/01

APPLICANT?S DESCRIPTION: UroCor, Inc., seeks to develop and optimize the technology of gene specific hypermethylation detection and determine the feasibiity of delivering diagnostic and/or prognostic methylation assays to the marketplace. The recognition that aberrant gene methylation plays an important role in carcinogenesis has increased in re...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/01/01 - 05/31/03

The p53 tumor suppressor gene regulates many physiologic pathways that are important in the development of cancer and is the gene most frequently observed to be mutated in metastatic cancers. As a result, p53 mutations in cancer cells indicate that the tumor containing such p53 mutated cells is at high risk for disease progression to a higher cl...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/99 - 08/31/00
PI: Gang An

Prostate cancer is the most frequently diagnosed malignancy and the second leading cause of cancer-related deaths in American males. No reliable markers that can be reliably applied to needle core tissue samples are currently available for either early diagnosis or correct prediction of progression of the disease. Development of better diagnosti...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/17/98 - 02/28/99

For bladder cancer, we seek to improve patient outcomes and reduce healthcare costs by delivering to the urological market an assay with enhanced ability to predict disease progression to an invasive or metastatic phenotype. Specifically, we will strive to validate and improve on an assay wit...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/98 - 07/31/99

DESCRIPTION: (Adapted from the investigator's abstract) Interstitial cystitis (IC), or non-bacterial cystitis, is a vaguely defined chronic inflammatory bladder uroepithelial syndrome responsible for a debilitated lifestyle in up to 450,000 patients in the U.S., 90% of which are women. Urologic diagnosis of I...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/15/93 - 03/14/94

A novel apparatus, the High Aspect Rotating-Wall Vessel (HARV), developed by NASA at the Johnson Space Center, Houston, TX, produces three dimensional cellular aggregates (spheroids) under low fluid shear conditIons, an aspect of simulated microgravity. The vessel rotates cells and culture medium in a disk-shaped chamber about a horizontal axis ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/05/93 - 02/28/94

A new and novel apparatus, the High Aspect Rotating-Wall Vessel (HARV), developed by NASA at the Johnson Space Center, Houston, TX, produces three dimensional cellular aggregates (spheroids) under low fluid shear conditions, an aspect of simulated microgravity. The vessel rotates cells and culture medium in a disk-shaped chamber about a horizon...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 03/01/93 - 09/30/93

CytoDiagnostics, Inc., (CDI) and the University of Oklahoma developed partially automated, user-interactive systems for quantitation of biomarkers used in the diagnosis of bladder cancer. The goal of this Phase I project is to demonstrate the feasibility of further automation with an online neural network system integrated with the quantitative...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/92 - 02/28/93

Cytoskeletal and nuclear matrix proteins (NMPs) play an important role in the bio-chemical events involved in differentiation and transformation of mammalian cells. Certain of these markers, F/G-Actin and bladder cancer- related NMPs, provide a unique means for early identification of bladder cancer as well as assessment of field disease effect...