Biotech Research Laboratories, Inc.

Rockville, MD 20850

SBIR Award Summary

Total Number of Awards 13
Total Value of Awards $0.0
First Award Date 04/01/85
Most Recent Award Date 09/01/93

Key Personnel

Last Name Name Awards Contact
Steuer Anton F Steuer 3
Corrigan Alice J Corrigan 1
Hao Yu-Lee Hao 2
Manak Mark M Manak 7

13 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/93 - 08/31/94

Studies conducted in the course of this grant are aimed at establishing the significance of PCR based assays for the diagnosis of pediatric HIV-1 infection and prediction of eventual progression to disease. A simple, rapid, reliable assay suitable for routine clinical testing will be developed and evaluated for the direct detection of HIV-1 seq...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/92 - 08/31/93

Studies conducted in the course of this grant are aimed at establishing the significance of PCR based assays for the diagnosis of pediatric HIV-1 infection and prediction of eventual progression to disease. A simple, rapid, reliable assay suitable for routine clinical testing will be developed and evaluated for the direct detection of HIV-1 seq...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/90 - 03/31/91

The treatment of Lyme disease could be greatly enhanced if it were possible to detect the lyme disease spirochete directly in blood, with a highly sensitive test. We propose to develop a test where a region of the B. burgdorderi ospA gene is amplified using the PCR to obtain the necessary sensitivity. The amplified product will be detected ini...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/90 - 01/31/91

Prevalence studies for HIV-1 infection in newborns are difficult to obtain since the commonly used antibody assays are not appropriate for testing babies. Babies carry the maternal antibody for up to 12-18 months after birth, so that all babies born to seropositive mothers will also test positive. Yet 40-50% of these babies are not actually in...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 03/01/89 - 08/31/89

Phase I funding will support the development of a prototype Elisa antigen capture kit to measure HTLV-1 is linked to the development of adult T- cell leukemia and to tropical spastic paraparesis, a neurological disease with interest to researchers on multiple sclerosis. Tracking the progress of HTLV-I infection in tissue cultures is more difficu...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/88 - 07/31/89

Our long-term objective is the development of cost-effective technology for the manufacture of vaccines and pharmaceuticals from animal cell culture. Our Phase I project demonstrated the feasibility of growing mammalian cells in porous microcarriers (PMC) made from collagen-glycosaminoglycan crosslinked copolymer. High densities of viable and m...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/87 - 08/31/88

Biotech has developed and is producing a number of products for the detection of antibodies to HTLV-III in human sera. The company has also developed non-radioactive techniques for tagging DNA probes with haptens, so that they may be detected using enzyme-linked antibodies. Such probes are potentially useful for the detection of viruses in inf...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/87 - 07/31/88

Our long-term objective is the development of cost-effective technology for the manufacture of vaccines and pharmaceuticals from animal cell culture. Our Phase I project demonstrated the feasibility of growing mammalian cells in porous microcarriers (PMC) made from collagen-glycosaminoglycan crosslinked copolymer. High densities of viable and m...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/86 - 08/31/87

Biotech has developed and is producing a number of products for the detection of antibodies to HTLV-III in human sera. The company has also developed non-radioactive techniques for tagging DNA probes with haptens, so that they may be detected using enzyme-linked antibodies. Such probes are potentially useful for the detection of viruses in inf...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/01/85 - 06/30/86

Pyrogenicity caused by the Gram-negative bacterial endotoxins has always been a serious problem in the plasma fractionation industry. Many a time, manufacturers find their final product pyrogenic prior to filling thus resulting in the loss of the entire lot of valuable material. It has been known for 30 years that normal human plasma (or serum...

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