Immune Complex Corporation

San Diego, CA 92121

SBIR Award Summary

Total Number of Awards 14
Total Value of Awards $904K
First Award Date 04/01/86
Most Recent Award Date 07/01/01

Key Personnel

Last Name Name Awards Contact
Tullis Richard H Tullis 4
Barnes Henry J Barnes 4
Birkett Ashley J Birkett 5
Johnson David A Johnson 1

14 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/01/01 - 06/30/02

Phase I work has resulted in the successful development of a candidate P.falciparum malaria vaccine. The vaccine is composed of well- characterized neutralizing B cell epitopes and a universal human T cell epitope delivered on a highly immunogenic particulate carrier protein that effectively delivers 240 copies of each epitope on each particle. ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/01/00 - 06/30/01

Phase I work has resulted in the successful development of a candidate P.falciparum malaria vaccine. The vaccine is composed of well- characterized neutralizing B cell epitopes and a universal human T cell epitope delivered on a highly immunogenic particulate carrier protein that effectively delivers 240 copies of each epitope on each particle. ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/10/00 - 08/10/00

The direct objective of this grant is to establish conditions in which Escherichia coli cells can be used co-expressing multi-gram quantities of cytochrome P450 metabolite(s). The technology is based on recombinant strains of E. Coli coexpressing individual cytochrome P450s and NADPH: cytochrome P450 reductase. Fermentation conditions will be op...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/28/98 - 08/31/99

Chronic rejection (CR) remains the primary cause of late graft loss following renal transplantation. Projections estimate that the 10-year survival rate for renal allografts is just 40 percent. While improved immunosuppresive therapy has decreased the occurrence of acute rejection, the percenta...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/98 - 02/29/00

Cytochrome P450 enzymes play a critical role in the metabolism of a wide variety of drugs and other ingested chemical compounds. These enzymes represent the first step in the metabolism of these chemicals; a process that yields products which have very different biological effects from the original compound. A k...

Unknown

Malaria Vaccine

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/98 - 01/31/99

Pre-erythrocytic stage malaria vaccines aim to block hepatocyte entry by sporozoites and/or release of merozoites into the blood stream, thereby circumventing the disease process and rendering the host non- infectious. The primary target of this class of vaccines is the circumsporozoite protei...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/97 - 08/31/98

Cytochrome P450 enzymes play a critical role in the metabolism of a wide variety of drugs and other ingested chemical compounds. These enzymes represent the first step in the metabolism of these chemicals; a process that yields products which have very different biological effects from the original compound. A k...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 02/01/97 - 01/31/98

DESCRIPTION: (Adapted from applicant's abstract) Recent advances in the chemoselective ligation of peptides has greatly increased the range of useful proteins that can be produced in this manner. The adaptation of this procedure to facilitate the internal insertion of designer synthetic peptides between recomb...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/18/96 - 03/17/97

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/94 - 06/30/95

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