Howard M. Shapiro, MD, P.c.

283 HIGHLAND AVE.
West Newton, MA 02465

SBIR Award Summary

Total Number of Awards 26
Total Value of Awards $1.17MM
First Award Date 01/01/84
Most Recent Award Date 05/01/08

Key Personnel

Last Name Name Awards Contact
Shapiro Howard M. Shapiro 26

26 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-34
Budget: 05/01/08 - 04/30/10

DESCRIPTION (provided by applicant): The World Health Organization (WHO) estimates that 8.9 million cases of TB occurred in 2004, with 3.9 million of these representing the most infectious, smear-positive, form. Of the estimated 1.7 million deaths, over 260,000 occurred in HIV-infected individuals; the increasing incidence of TB worldwide is due...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-20
Budget: 07/01/07 - 12/31/07

DESCRIPTION (provided by applicant): In late 1981, Gottlieb et al described an apparently new immunodeficiency syndrome in homosexual men living in the United States. We now know the syndrome as AIDS (Acquired Immune Deficiency Syndrome), recognize the retrovirus HIV (Human Immunodeficiency Virus) as its cause, and describe the involved cell su...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/01/05 - 05/30/06

DESCRIPTION (provided by applicant): Blood platelets collected for transfusion must be stored at room temperature to maximize their survival in a functional state. Bacteria may be introduced into stored platelets during the collection process or as a result of unnoticed bacteremia in the donor(s); room temperature storage is substantially more ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 03/15/05 - 02/28/06

DESCRIPTION (provided by applicant): Tuberculosis (TB) remains one of the deadliest diseases, with more than 8 million new cases and approximately 3 million deaths worldwide annually. Since the 1980s, increased incidence of active TB in HIV-infected individuals and the emergence of drug-resistant strains of Mycobacterium tuberculosis have int...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 03/01/04 - 10/31/04

DESCRIPTION (provided by applicant): Most flow cytometers are optimized for analysis of eukaryotic cells. Measurements of bacteria and viruses in conventional instruments are limited by photoelectron statistics; some microbial constituents, and smaller microbes, may thus be undetectable or not measurable with precision. In this project, a ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PAR-98-073
Budget: 03/01/01 - 08/31/01

DESCRIPTION (provided by applicant): There has recently been an alarming increase in infections due to bacteria resistant to all available antibiotics. Tetracycline resistance is typically mediated by efflux pumps; tetracycline derivatives which inhibit them may be used in combination with existing tetracy...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/00 - 07/31/02

Although flow cytometers have become indispensable to researchers in many areas of biology and medicine who study the normal and abnormal behavior of cells, acquisition costs of apparatus remain high. Recent advances in laser, reagent and electronic technology now make it possible to build multiparameter flow cytometers using inexpensive diode ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/99 - 08/31/00

Although flow cytometers have become indispensable to researchers in many areas of biology and medicine who study the normal and abnormal behavior of cells, acquisition costs of apparatus remain high. Recent advances in laser, reagent and electronic technology now make it possible to build multiparameter flow cytometers using inexpensive diode ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 03/15/98 - 09/14/98

DESCRIPTION: (Adapted from the Applicant's Abstract): This project will develop a new generation of comparatively low cost analog and hybrid signal processing electronics, data acquisition hardware, and software suitable for incorporation into flow cytometers. The project will further examine th...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/96 - 03/31/97

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