Immtech International, Inc.

Vernon Hills, IL 60061

SBIR Award Summary

Total Number of Awards 11
Total Value of Awards $1.08MM
First Award Date 07/01/88
Most Recent Award Date 08/01/04

Key Personnel

Last Name Name Awards Contact
Potempa Lawrence A Potempa 4
Makhlouf Samar E Makhlouf 3
Reisner Howard M Reisner 1
Boykin David W Boykin 1
Allen James L Allen 2

11 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/04 - 04/30/05

DESCRIPTION (provided by applicant): The long-range research goal is to develop a new drug to treat secondary (central nervous system) stage human African trypanosomiasis. Previous SBIR supported research identified DB289, a methoxime prodrug of the aromatic dication furamidine, that is currently progressing in Phase lib clinical trials for trea...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/01 - 08/31/02

The long-range goal is to develop new drugs to treat important AIDS-related opportunistic infections and tropical parasitic diseases. STTR Phase I studies confirmed the hypothesis that diamidoxime prodrugs are readily absorbed after oral administration, then metabolized to active diamidines, with excellent antimicrob...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/00 - 08/31/01

The long-range goal is to develop new drugs to treat important AIDS-related opportunistic infections and tropical parasitic diseases. STTR Phase I studies confirmed the hypothesis that diamidoxime prodrugs are readily absorbed after oral administration, then metabolized to active diamidines, with excellent antimicrob...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/00 - 08/31/01

The long range goal of the research is to develop new, highly active drugs to treat important AIDS-associated opportunistic pathogens, including the intestinal protozoan parasite Cryptosporidium parvum and the fungal pathogens Pneumocystis carinii, Candida albicans and Cryptococcus neoformans. SBIR Phase I studies have identified a lead candida...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/99 - 08/31/00

The long range goal of the research is to develop new, highly active drugs to treat important AIDS-associated opportunistic pathogens, including the intestinal protozoan parasite Cryptosporidium parvum and the fungal pathogens Pneumocystis carinii, Candida albicans and Cryptococcus neoformans. SBIR Phase I studies have identified a lead candida...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 06/01/98 - 05/31/99

DESCRIPTION: (adapted from applicant's abstract) Pentamidine, a dication employed for decades to treat the tropical infectious leishmaniasis and African trypanosomiasis, remains useful for the treatment of antimony resistant leishmaniasis, primary stage human African trypanosomiasis...

Phase 1 STTR

Agency: Department of Health & Human Services
Topic:
Budget: 02/01/98 - 01/31/99

DESCRIPTION: (Adapted from the applicant's abstract) Pentamidine [1,5- bis(4-amidinophenoxy)pentane] is the exemplar of a growing class of dicationic, aromatic agents active against a variety of infectious agents of significance to immunocompromised and normal individuals. Pentamidine is still an...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/94 - 03/31/95

Alcohol usage over time results in a number of metabolic alterations including the production and secretion into the blood of increased quantities of pI 5.7 and 5.9 isoforms of transferrin. These transferrin isoforms (TIs) can be detected by isoelectric focusing and their quantities directly correlate with the amount of alcohol intake by an ind...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/93 - 03/31/94

Alcohol usage over time results in a number of metabolic alterations including the production and secretion into the blood of increased quantities of pI 5.7 and 5.9 isoforms of transferrin. These transferrin isoforms (TIs) can be detected by isoelectric focusing and their quantities directly correlate with the amount of alcohol intake by an ind...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/01/90 - 11/30/90

Alcohol usage over time results in a number of metabolic alterations to several organ systems including changes in liver function. One of the latter changes is the production and secretion into the blood of an isoform of the transferrin molecule. The pI 5.7 transferrin isoform can be detected by isoelectric focusing and its quantities have bee...

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