University Medical Associates

Louisville, KY 40202

SBIR Award Summary

Total Number of Awards 10
Total Value of Awards $0.0
First Award Date 09/01/86
Most Recent Award Date 09/30/94

Key Personnel

Last Name Name Awards Contact
Klein Elias Klein 4
Ward Richard Ward 3
Harris Eon Nigel Harris 3

10 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/94 - 06/30/95

More than 100,000 patients now receive chronic hemodialysis therapy in Medicare's End Stage Renal Disease Program. Hemodialysis related amyloidosis affects a significant portion of these patients. The syndrome presents clinically as carped tunnel syndrome, cystic bone lesions, and arthropathies. The disorder has been identified with excessive...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/93 - 03/31/94

The AntiPhospholipid Syndrome (APS) is a disorder of recurrent arterial or venous thromboses and recurrent fetal loss affecting a small population of young people. These patients are identified by production of relatively high levels of antibodies specific for negatively charged phospholipids. An ELISA assay system using cardiolipin as antigen ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/15/92 - 03/31/93

The AntiPhospholipid Syndrome (APS) is a disorder of recurrent arterial or venous thromboses and recurrent fetal loss affecting a small population of young people. These patients are identified by production of relatively high levels of antibodies specific for negatively charged phospholipids. An ELISA assay system using cardiolipin as antigen ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/89 - 12/31/90

Hemodialysis is widely used to sustain life in individuals without kidney function. The membrane material most commonly used for this purpose is regenerated cellulose. Regenerated cellulose is not completely biocompatible; it stimulates the coagulation and complement systems and may be a cause of both acute and chronic morbidity for the patien...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/01/89 - 12/31/89

In some patients, phospholipid binding antibodies have been associated with recurrent venous and/or arterial thrombosis as well as with recurrent fetal loss (the "Antiphospholipid Syndrome" (APS)). These antibodies are induced in a variety of clinical circumstances and it is likely that the above clinical associations are limited only to patien...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/89 - 12/31/90

Peritoneal dialysis used in treating patients with end-stage renal disease utilizes the osmotic force of high concentrations of glucose to transfer water from the body pool to the dialysate as a substitute for urinary excretion. The high glucose content of the dialysate has been identified as a source of several metabolic problems in such patie...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/88 - 07/31/89

Hemodialysis is widely used to sustain life in individuals without kidney function. The membrane material most commonly used for this purpose is regenerated cellulose. Regenerated cellulose is not completely biocompatible; it stimulates the coagulation and complement systems and may be a cause of both acute and chronic morbidity for the patien...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 05/01/88 - 03/31/89

Peritoneal dialysis used in treating patients with end-stage renal disease utilizes the osmotic force of high concentrations of glucose to transfer water from the body pool to the dialysate as a substitute for urinary excretion. The high glucose content of the dialysate has been identified as a source of several metabolic problems in such patie...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/15/86 - 04/05/87

Hemodialysis is widely used to sustain life in individuals who have lost kidney function. The membrane material most commonly used for this purpose is regenerated cellulose. Regenerated cellulose is not inert; it stimulates the coagulation and complement systems and may be a cause of both acute and chronic morbidity for the patient. Further, ...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/86 - 04/05/87

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