Anticancer, Inc.

San Diego, CA 92111
http://anticancer.com/

SBIR Award Summary

Total Number of Awards 47
Total Value of Awards $6.83MM
First Award Date 09/15/86
Most Recent Award Date 12/15/16

Key Personnel

Last Name Name Awards Contact
Stern Peter Stern 2
Fakhrai Habib Fakhrai 1
Fu Xinyu Fu 3
Li Lingna Li 6
Monosov Ann Z Monosov 1
Monosov Anna Z Monosov 1
Lishko Valeryi K Lishko 2
Wang Xiaoen Wang 3
Guo Huiyan Guo 2
Yang Meng Yang 12
Tan Yuying Tan 7
Zhao Ming Zhao 5
Kishimoto Hiroyuki Kishimoto 1
HOFFMAN ROBERT M HOFFMAN 1

47 Awards Won

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-15-269
Budget: 12/15/16 - 11/30/17

Project Summary/Abstract: Soft-tissue sarcoma (STS) is a recalcitrant group of malignancies with over 50 distinct histologic subtypes. Patient-derived mouse models of the representative STS subtypes that recapitulates disease progression and metastasis optimize the potential for individualizing STS therapy and for discovery of more effective the...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-13-234
Budget: 07/15/14 - 08/31/15
PI: Lingna Li

DESCRIPTION (provided by applicant): Nestin-expressing stem cells of the hair follicle, discovered by our laboratory (Proc Natl Acad Sci USA 2003;100:9658-61[1]), have been shown by our laboratory to be able to form neurons and other non-follicle cell types (Proc Natl Acad Sci USA 2005;102:5530-4 [2]). Our laboratory has shown that the nestin-ex...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-13-234
Budget: 07/15/14 - 06/30/15
PI: Meng Yang

DESCRIPTION (provided by applicant): Individualized cancer treatment is an important goal, in particular, for pancreatic cancer, which is the most lethal human cancer. Novel transformative therapeutics are also urgently needed to cure this disease. Our laboratory pioneered the orthotopic growth of patient tumors, including colon cancer (1) and p...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-09-080
Budget: 06/14/11 - 05/31/12
PI: Ming Zhao

DESCRIPTION (provided by applicant): We have developed an effective bacterial cancer therapy strategy by targeting viable tumor tissue by using Salmonella typhimurium auxotrophs that we have generated which grow in viable as well as necrotic areas of tumors. However, the auxotrophy severely restricts growth of these bacteria in normal tissue ena...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-09-080
Budget: 06/01/10 - 05/31/11
PI: Ming Zhao

DESCRIPTION (provided by applicant): We have developed an effective bacterial cancer therapy strategy by targeting viable tumor tissue by using Salmonella typhimurium auxotrophs that we have generated which grow in viable as well as necrotic areas of tumors. However, the auxotrophy severely restricts growth of these bacteria in normal tissue ena...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-07-80
Budget: 06/13/08 - 05/31/09

DESCRIPTION (provided by applicant): We are developing a new approach to image tumors by selectively targeting the tumors in vivo with a telomerase-specific replication-competent adenovirus expressing green fluorescent protein (GFP) (OBP-401). OBP-401 contains a replication cassette in which the human telomerase reverse transcriptase (hTERT) pro...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-20
Budget: 09/21/07 - 08/31/08
PI: Ming Zhao

DESCRIPTION (provided by applicant): The goal of this application is to develop imageable tumor-targeting bacteria that can cure tumors without progressive infection of the host. Previous experiments by others employed anaerobic microorganisms for cancer therapy. Target specificity appeared largely due to the anaerobic requirements met principal...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-06
Budget: 09/04/07 - 08/31/08
PI: Meng Yang

DESCRIPTION (provided by applicant): There is a need for clinically-relevant imageable animal models of tumor blood flow, intravascular cancer-cell trafficking and extravasation, critical targets for current drug evaluation and development. Most models of tumor cell trafficking and blood flow are either based on subcutaneous transplantation of t...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PA-06-06
Budget: 08/01/07 - 07/31/08
PI: Meng Yang

DESCRIPTION (provided by applicant): The facile availability of pluripotent adult stem cells would have many important therapeutic applications. Our recent results suggest that the hair follicle is a promising source for such stem cells. Our discovery that the neural stem cell marker nestin is expressed in hair follicle bulge area cells, the sit...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 05/01/07 - 04/30/08
PI: Meng Yang

DESCRIPTION (provided by applicant): This Phase II application will further develop dual-color imageable tumor-host-interaction nude mouse models, developed in the Phase I application, to be used in Phase III to discover and evaluate new effective agents for stromal therapy, including angiogenesis. The host models are the ubiquitously-expressing...

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