Biological Research Faculty &facility

Ijamsville, MD 21754

SBIR Award Summary

Total Number of Awards 10
Total Value of Awards $0.0
First Award Date 06/01/86
Most Recent Award Date 04/01/94

Key Personnel

Last Name Name Awards Contact
Iype P Thomas Iype 8
Shivapurkar Narayan M Shivapurkar 1
Kaighn Morris E. Kaighn 1

10 Awards Won

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/94 - 03/31/96

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 04/01/93 - 03/31/94

The long-term objective of this project is to establish screening systems for chemicals that produce mutations in important regulatory DNA sequences of mammalian cells at low levels of exposure. During the Phase I study, the ability of different classes of toxic chemicals to induce mutations in ras proto-oncogenes in rat liver epithelial cell c...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/01/92 - 12/31/92

The overall objective of this project is to include human prostatic cancer cell lines for discovering cancer chemotherapeutic drugs. Specific aims of Phase I include establishment and characterization of new human prostatic cancer cell strains/lines suitable for drug evaluation. These studies will include the use of special culture media and ex...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 03/16/92 - 09/15/92

DESCRIPTION: (Investigator's Abstract): The overall objective of this Phase I proposal is to develop a new Syrian Hamster Embryo (SHE) Morphological Transformation Assay (MTA) employing specific cell types as targets and using defined, serum-free culture media. Specific aims for Phase I study include: (1) isolation and characterization of sp...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/01/91 - 12/31/91

DESCRIPTION: (Adapted from the applicant's abstract) The ultimate objective of this project is to develop new methodologies to measure and distinguish between cytotoxicity and growth inhibition by toxic chemicals, carcinogenic agents and chemotherapeutic drugs. The specific aims include: (a) To establish the feasibility of measuring cell numbe...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/01/90 - 12/31/90

The long-term objective of this project is to develop a laboratory test for monitoring low level toxicity from chemical exposure at levels which do not produce acute symptoms such as cytotoxicity, but which produce detectable damage later. The specific aims for the Phase I investigations are: (a) To determine the sub cytotoxic levels of three ...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/89 - 11/30/90

The long-term objective of this project is to establish a stable source of a pure endogenous hepatic proliferation inhibitor (HPI) and other related modulators of cell division. These important probes can then be made available for fundamental research into the regulation of cell proliferation and differentiation, which may be a common denomina...

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/88 - 07/31/89

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 08/01/88 - 07/31/89

The long-term objective of this project is to establish a stable source of a pure endogenous hepatic proliferation inhibitor (HPI) and other related modulators of cell division. These important probes can then be made available for fundamental research into the regulation of cell proliferation and differentiation, which may be a common denomina...

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 06/01/86 - 11/30/86

The long-term objective of this project is to establish a stable source of a pure endogenous hepatic proliferation inhibitor (HPI) and other related modulators of cell division. These important probes can then be made available for fundamental research into the regulation of cell proliferation and differentiation, which may be a common denomina...

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