| Last Name | Name | Awards | Contact | |
|---|---|---|---|---|
| Benner | Steven Benner | 11 | Message | |
| Hughes | Romaine Hughes | 1 | Message | |
| Leal | Nicole Leal | 1 | Message | |
| Hutter | Daniel Hutter | 4 | ||
| Benner | Steven Benner | 1 | Message | |
| DAME | JOHN B. DAME | 1 | ||
| HOSHIKA | SHUICHI HOSHIKA | 1 | ||
| ELLINGTON | ANDREW D ELLINGTON | 1 | ||
| YANG | ZUNYI YANG | 1 |
Phase 1 SBIR
Phase 2 STTR
Receptors, Ligands, and Catalysts on Demand using Expanded Genetic Alphabets Firebird Biomolecular Sciences, LLC. The Foundation for Applied Molecular Evolution The Scripps Research Institute Steven A. Benner Zunyi Yang Brian Paegel ABSTRACT Technology to deliver ?on demand? molecules that bind targets or catalyze reactions of choice has b...
Phase 1 STTR
Commercial Polymerases to Create Receptors, Ligands, and Catalysts on Demand Firebird Biomolecular Sciences LLC University of Texas Steven A. Benner Andrew D. EllingtonABSTRACT Innovators at Firebird Biomolecular Sciences LLC have created several generations of an ?artificially ex-panded genetic information system? (AEGIS) that adds eight nucleo...
Phase 1 STTR
? DESCRIPTION (provided by applicant): To many (notably Craig Venter), synthetic biology means simply synthesizing large amounts of DNA. This type of synthetic biology actually began in the 1980's, when Caruthers introduced a phosphoramidite-based solid phase DNA synthesis architecture. This allowed ICI and the Benner group to synthesize compl...
Phase 1 SBIR
Eliminating Malaria from Haiti. Reinventing DNA to Eradicate Endemic Parasites Firebird Biomolecular Sciences LLC University of Florida Steven A. Benner John B. DameAbstract Eradication of Plasmodium falciparum, the parasite that causes the most malarial deaths, is the only way tofinally treat the disease in any specific geographical region. Hai...
Phase 1 STTR
DESCRIPTION (provided by applicant): Technology to deliver molecules "on demand" that bind to targets or catalyze reactions of a technologist's choosing would have enormous commercial value in research, manufacturing, and medicine. Thus, this has been a "holy grail" of molecular science for a half century. Even today, chemical theory is inadequ...
Phase 1 SBIR
DESCRIPTION (provided by applicant): The public health challenges from RNA viruses are at a tipping point, with dengue moving up Florida, human transmission of chickungunya now established in Florida, and, transmitted by different mechanism, Ebola. While these have long been a challenge, their incidence has been predominantly overseas. In addit...
Phase 1 STTR
DESCRIPTION (provided by applicant): Only a few inexpensive drugs can be used in the developing world for the treatment of AIDS. Several of these target the HIV reverse transcriptase (RT). Accordingly, patient therapy with these drugs often fails when the gene encoding RT undergoes mutation. Thus, the WHO recently reported that after 12 months o...
Phase 1 SBIR
Firebird will deliver a hand-held CLIA-waivable battery-powered device that will allow point-of-need detection of norovirus RNA, with a fluorescence readout excited by a battery-powered LED. The readout can be interpreted at the point-of-need, or transmitted by cell phone to a distant site. This devise is possible only through the application of...
Phase 2 STTR
Institution: FfAME
Because of chemical behaviors of real DNA molecules, the nanotechnology envisioned by the Defense Department in this Solicitation will be possible only if design automation software creates nanostructures that exploit artificially expanded genetic information systems (AEGIS). AEGIS DNA molecules have more than the four nucleotides (GACT) found i...
