Awards

Unknown

Novel Detection Methodology for Lyme Disease Targets

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 03/01/97 - 11/30/97
PI: Scott Allan Lesley

Early, definitive detection of pathogenic agents often is key to effective treatment and full recovery. Although DNA and protein-based detection systems are widely used to detect pathogen and disease markers, a number of systems have limited capacity to rapidly produce reagents specific for existing a...

Unknown

Tools for Studying Eukaryotic Cell Membrane Trafficking

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 02/01/97 - 01/31/98
PI: Alexey G Zdanovsky

DESCRIPTION (Adapted from applicant's abstract): Clostridial neurotoxins (NTs) have been extremely valuable for elucidating the mechanisms of neurotransmitter secretion from nerve cells since eight distinct NTs were found to act as specific proteases on only three neurosynaptic proteins: synaptobrevin, syntaxin...

$750K

An Engineered RNA/DNA Polymerase to Increase Speed and Economy of DNA Sequencing

Phase 2 SBIR

Agency: Department of Energy
Topic: 1997
Budget: 01/01/97 - 12/31/97
PI: Dr. Mark W. Knuth

41294 November 19, 1996

$299K

USING MULTIPLEXED LUMINESCENCE TO EXTEND BIOASSAY CAPABILITIES

Phase 2 SBIR

Agency: National Science Foundation
Topic: 1997
Budget: 01/01/97 - 12/31/97
PI: Keith Wood

CURRENT LUMINESCENCE BIOASSAYS RELY SOLELY UPON MESUREMENT OF LUMINESCENCE INTENSITY TO GENERATE INFORMATION. MULTIPLE COLORS FROM BEETLE LUCIFERASE HAS CREATED THE OPPORTUNITY TO INCREASE ASSAY INFORMATION CONTENT BY USING MULTIPLEXING TECHNIQUES TO MEASURE LIGHT INTENSITIES AT DIFFERENT WAVELENGTHS. THIS PROVIDES GREATER ASSAY RELIABILITY, PRE...

$99.9K

The Design and Synthesis of Orally Active Inhibitors of Botilinum Toxin metalloproteases

Phase 1 SBIR

Agency: Army
Topic: A96-138
Budget: 11/22/96 - 05/22/97
PI: Dr. Alexey G. Zdanovsky

Unknown

Ribonuclease Inhibitors

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/01/96 - 05/31/97
PI: John W Shultz

Unknown

Novel Polymorphic Markers for Genetic Analyses

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/01/96 - 06/30/97
PI: James W Schumm

Unknown

Novel Beetle Luciferases for Biomedical Development

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 07/01/96 - 12/31/97
PI: Keith V Wood

$75K

An Engineered RNA/DNA Polymerase to Increase Speed and Economy of DNA Sequencing

Phase 1 SBIR

Agency: Department of Energy
Topic: 1996
Budget: 01/01/96 - 12/31/96
PI: Dr. Mark W. Knuth

Unknown

Developing Technologies for Studying Protein Prenylation

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/30/95 - 09/30/96
PI: Erik M Schaefer

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