Awards

$231K

Optical Dosimeter-guided Photodynamic Therapy

Phase 1 SBIR

Agency: Department of Health & Human Services
Topic: PA-15-269
Budget: 01/01/17 - 12/31/17
PI: Dr. Steven J. Davis

Photodynamic Therapy (PDT) is a promising modality for cancer treatment. Oxygen molecules in the metastable singlet delta state O2(1?) are believed to be the species that destroys cancerous cells during PDT. Despite the benefit of targeted PDT that kills tumors selectively with minimum effect on surrounding healthy tissues, at the present time i...

$1.51MM

High Performance, Semi-Solid Monopropellant for Advanced Low Cost Expendable Launch Vehicles

Phase 2 SBIR

Agency: Department of Defense
Topic: SB152-008
Budget: 09/30/16 - 09/29/18
PI: Dr. Allan Dokhan

Physical Sciences Inc. proposes to demonstrate and quantify a novel, safe, high density impulse, green storable liquid propellant in a rocket engine. This new propellant formulation can be treated as a monopropellant or as a bipropellant system with predicted specific impulse and density specific impulses exceeding NTO/MMH performance. The liqui...

$1000K

Hand-held minimally invasive optical probe for three-dimensional visualization of intraocular anatomy and morphology

Phase 2 SBIR

Agency: Department of Defense
Topic: DHP15-016
Budget: 09/29/16 - 02/28/19
PI: Dr. Nicusor V. Iftimia

Intraocular surgery is usually performed under stereoscopic guidance using a surgical microscope. The surgeon is usually able to see intraocular structures through a clear cornea. However, when the optical clarity of the cornea is severely compromised, visualization of the retina and other intraocular structures is very difficult or impossible. ...

$1000K

Bio-MAV Development

Phase 2 SBIR

Agency: Army
Topic: A13-098
Budget: 09/26/16 - 09/25/17
PI: Julia R. Dupuis

Physical Sciences Inc. (PSI) proposes to develop an unmanned aircraft system based bioaerosol detection capability that is cued to a region of interest using non-specific, persistent and wide area thermal imagers commonly deployed for surveillance. The detection capability, referred to as Bio-MAV, will fold into a recursive Bayesian classifier ...

$1MM

Real-Time Health Management Portable Sensor for Solid Rocket Motors

Phase 2 STTR

Institution: Pennsylvania State University

Agency: Department of Defense
Topic: MDA14-T004
Budget: 09/20/16 - 09/19/18
PI: Dr. Allan Dokhan

Physical Sciences Inc. (PSI) proposes to design, develop, and demonstrate a portable, non-invasive, real-time sensor to assess the chemical and physical health of solid rocket motors as a function of age without affecting the motors integrity nor having direct contact with the propellant. In Phase II, a sensor to monitor specific gas species tha...

$1.5MM

Igf::ot::igf: Sbir Phase Ii, Topic 331: Optical Biosensor for Real-time Assessment of Tumor Cellularity During Core Needle Biopsy Procedures.

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic:
Budget: 09/19/16 - 09/18/18
PI: Dr. Nicusor V. Iftimia

The long term goal of this program is to develop and translate to clinical use a novel technology that will help interventional radiologists to improve the success rate of the core needle biopsy procedures. Although ultrasound or CT are used to identify tumor location and thus to guide biopsy needle insertion, these technologies do not provide t...

$978K

Electronic Infrared Flare: Technology Preparation for Engineering and Manufacturing Development

Phase 2 SBIR

Agency: Army
Topic: A09-004
Budget: 09/16/16 - 09/15/17
PI: Dr. David B. Oakes

In this Subsequent Phase II SBIR proposal Physical Sciences Inc. outlines the continued development of its electronic infrared (IR) flare illuminator technology that meets the Armys specifications for the M-278 IR flare while overcoming documented safety and reliability issues with the current chemical (illuminant) based IR flare. Specifically, ...

$99.9K

Multimodal Trace Explosives Detection with Feature-Based Fusion

Phase 1 SBIR

Agency: Army
Topic: A16-011
Budget: 09/08/16 - 03/07/17
PI: Dr. Christian Smith

Physical Sciences Inc. proposes to develop a multimodal system for long-range standoff (50m) trace explosives detection and interrogation with sensitivity in the microgram to nanogram range. The technology will rely on data fusion between multiple sensors, including initial aerial anomaly detection, and follow on standoff explosives mapping and...

$609K

Compressive Sensing Flash IR 3D Imager

Phase 2 STTR

Institution: Colorado State University

Agency: Army
Topic: A15A-T007
Budget: 09/07/16 - 08/31/17
PI: Julia R. Dupuis

Physical Sciences Inc. in collaboration with Colorado State University proposes to develop a compact infrared flash 3D imaging sensor employing compressive sensing (CS) approaches. The CS 3D sensor offers a combination of high range resolution (10 cm), high point cloud density (6464 format), and fast 3D image frame rates (10 Hz) in a low cost, c...

$491K

TDLAS-based SMART Freeze Dryer Process Development Technology

Phase 2 SBIR

Agency: Department of Health & Human Services
Topic: PAR-14-088
Budget: 09/01/16 - 08/31/17
PI: Mr. William J. Kessler

? DESCRIPTION (provided by applicant): Physical Sciences Inc. in collaboration with the University of Connecticut and SP Scientific will develop a combined hardware/software product that will enable pharmaceutical scientists to rapidly develop robust product freeze drying cycles on both laboratory and production scale lyophilizers. The produc...

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