Verification and Monitoring of Chemical Agents by Threshold Ionization Mass Spectrometry

Period of Performance: 08/21/1998 - 08/21/2000


Phase 2 SBIR

Recipient Firm

Syagen Technology, Inc.
Tustin, CA 92780
Principal Investigator

Research Topics


The Phase I program successfully demonstrated the proposed technique of laser threshold ionization mass spectrometry for real-time analysis of complex, multicomponent mixtures that included chemical warfare agent (CWA) simulants and precursors. The new technology greatly exceeds the requirements for a sample screening monitoring system chemical weapons convention (CWC) challenge inspections. It also exceeds the performance specifications for gas chromatography/electron ionization-mass spectrometry (GC/EI-MS) in nearly all relevant areas, and could ultimately fulfill the role as a real-time verification monitoring system. An instrument design is proposed for Phase Ii that should achieve sub-ppb and