Cyanide Poisoning Prophylactics

Period of Performance: 03/15/1993 - 03/14/1995

$533K

Phase 2 SBIR

Recipient Firm

Symbiotech, Inc.
8 FAIRFIELD BLVD, #3
Wallingford, CT 06492
Principal Investigator

Research Topics

Abstract

There is a need to develop pretreatment agents to counter chemical warfare gases such as hydrogen cyanide. The proposed work aims to develop cyanide antagonists that may be self-administered in low doses by troops. Novel polymers with the capacity to bind and detoxify lethal doses of cyanide will be synthesized and tested in vitro. Based on preliminary results, these novel cyanide antagonists are anticipated to covercome many of the problems presently encountered when using therapeutic agents from providing prophylaxis against cyanide poisoning.