STTR Phase II: Monolithic Multiwavelength Blue-to-IR LED for Biomedical Diagnostics

Period of Performance: 01/01/2009 - 12/31/2009

$500K

Phase 2 STTR

Recipient Firm

Valencell, Inc.
2800-154 sumner blvd
Raleigh, NC 27616
Principal Investigator

Research Institution

North Carolina State University
Campus Box 7514
Raleigh, NC 27695
Institution POC

Abstract

This Small Business Technology Transfer (STTR) Phase II project, in collaboration with North Carolina State University, will develop and validate an innovative, mobile, multiwavelength pulse oximetry module for noninvasive health monitoring of various blood metabolites simultaneously in real time. At the heart of this pulse oximetry module will be a novel multiwavelength emitter having independent control of up to nine spectrally narrow wavelengths, ranging from blue to mid-IR, emitting from a single 1 mm2 LED die. In contrast with traditional dual-wavelength pulse oximetry, which measures oxygen saturation in the blood, the proposed multiwavelength LED will enable real-time analysis several additional metabolites critical to health monitoring via the same noninvasive paradigm. Furthermore, the individually controlled self-aligned wavelengths enable superior motion artifact cancellation, which is essential for eHealth and mobile fitness applications. The key objectives of this feasibility study are to: Demonstrate luminescent films with peak emissions from 400-1100 nm Integrate these films into a compact multiwavelength pulse oximetry module Optimize novel pulsing algorithms for multiwavelength pulse oximetry Validate the mobile multiwavelength pulse oximetry module in a lab setting The medical impact of dual-wavelength pulse