SBIR Phase I: Immunological Tools for Trimetasphere Fullerenes

Period of Performance: 01/01/2006 - 12/31/2006

$100K

Phase 1 SBIR

Recipient Firm

Luna Innovations, Inc.
301 1st St Suite 200
Roanoke, VA 24011
Principal Investigator
Firm POC

Abstract

This Small Business Innovative Research (SBIR) Phase I project will address the production, characterization and application of antibodies to carbonaceous nanomaterials. Specifically, these are the trimetallic endohedral fullerene, Trimetaspheres (TMS). The project will develop the novel nanomaterials and produce immunoprobes and affinity matrices based on monoclonal and polyclonal anti-TMS antibodies. These will be used to evaluate the effects of the TMS as contrasting and therapeutic agents. The immunological tools developed will play an important role in the development and use of the TMS as contrasting and therapeutic agents. The use of these tools will expand the scientific and technological understanding of the chemistry, cell-mediated responses and the pharmacokinetics of these innovative TMS reagents.