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Top Investors in High-Technology

SBIR Source analyzes startup funding from both Federal R&D grants and Venture Capital sources to identify private equity investors that are most actively investing in high-technology firms. To calculate our ranking we take into consideration the volume of deals for each firm, as well as the percentage of their portfolio that has received Federal R&D dollars.

KEY
  • Defense
  • Health
  • Energy
  • Science
  • Space
  • Other
Rank Name % Portfolio SBIR Supported Sectors
1 Harris & Harris Group
New York, NY
50%
 
 
 
 
 
2 Lux Capital
New York, NY
44%
 
 
 
 
 
3 In-Q-Tel
Arlington, VA
30%
 
 
 
 
 
 
4 Syngenta Ventures
Basel, CH
50%
 
 
 
5 MedImmune Ventures
Gaithersburg, MD
39%
 
6 CalCEF Clean Energy Angel Fund
San Francisco, CA
50%
 
 
 
7 Stata Venture Partners
Needham Heights, MA
38%
 
 
 
8 Osage University Partners
Bala Cynwyd, PA
32%
 
 
 
 
9 Fletcher Spaght Ventures
Boston, MA
40%
 
 
 
10 Novartis Venture Funds
Cambridge, MA
32%
 
 
11 Kleiner Perkins Caufield & Byers
Menlo Park, CA
6%
 
 
 
 
12 InterSouth Partners
Durham, NC
22%
 
 
 
 
13 Draper Fisher Jurvetson (DFJ)
Menlo Park, CA
6%
 
 
 
 
 
 
14 Applied Ventures
Santa Clara, CA
29%
 
 
 
15 Sevin Rosen Funds
Dallas, TX
18%
 
 
 
 
 
16 MPM Capital
Boston, MA
21%
 
17 TPG Biotech
San Francisco, CA
33%
 
 
 
18 US Venture Partners
Menlo Park, CA
9%
 
 
 
 
 
19 Morningside Venture Investments
26%
 
 
 
20 Northwater Capital
Toronto, CA
29%
 
 
21 CIT GAP Funds
Herndon, VA
25%
 
 
 
22 Claremont Creek Ventures
Oakland, CA
22%
 
 
 
 
 
23 Khosla Ventures
Menlo Park, CA
8%
 
 
 
 
24 BioGenerator
St. Louis, MO
27%
 
25 CIT GAP Funds
Herndon, VA
19%
 
 
 
26 Mitsui Global Investment
New York, NY
23%
 
 
 
 
27 New Enterprise Associates
Menlo Park, CA
3%
 
 
 
 
28 Aberdare Ventures
San Francisco, CA
19%
 
 
29 Intel Capital
Santa Clara, CA
3%
 
 
 
 
 
30 Innovation Works
Pittsburgh, PA
16%
 
 
31 Domain Associates
Princeton, NJ
12%
 
 
 
32 Mohr Davidow Ventures
Menlo Park, CA
8%
 
 
 
 
 
33 Silicon Valley Bank
Santa Clara, CA
7%
 
 
 
 
34 Canaan Partners
Menlo Park, CA
6%
 
 
 
 
35 Siemens Venture Capital
Munich, DEU
11%
 
 
 
 
 
36 SV Life Sciences
Boston, MA
10%
 
 
 
37 Accuitive Medical Ventures
Palo Alto, CA
18%
 
38 North Bridge Venture Partners
Waltham, MA
6%
 
 
 
 
39 Connecticut Innovations
Rocky Hill, CT
8%
 
 
 
 
40 New Leaf Venture Partners
New York, NY
10%
 
41 Silicon Valley Bank
Santa Clara, CA
7%
 
 
 
 
42 SCP Vitalife Partners
Wayne, PA
17%
 
43 Golden Seeds
New York, NY
11%
 
 
 
44 Novo A/S
Hellerup, DK
10%
 
45 DAG Ventures
Palo Alto, CA
5%
 
 
 
 
 
 
46 Delphi Ventures
Menlo Park, CA
9%
 
 
47 Lightspeed Venture Partners
Menlo Park, CA
2%
 
 
48 Google Ventures
Mountain View, CA
2%
 
 
49 Index Ventures
London, UK
2%
 
 
50 Highland Capital Partners
Menlo Park, CA
2%
 
 
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